Neurofibromin-deficient myeloid cells are critical mediators of aneurysm formation in vivo.

Li, Fang; Downing, Brandon D; Smiley, Lucy C; Mund, Julie A; Distasi, Matthew R; Bessler, Waylan K; Sarchet, Kara N; Hinds, Daniel M; Kamendulis, Lisa M; Hingtgen, Cynthia M; Case, Jamie; Clapp, D Wade; Conway, Simon J; Stansfield, Brian K; Ingram, David A

Li, Fang; Downing, Brandon D; Smiley, Lucy C; Mund, Julie A; Distasi, Matthew R; Bessler, Waylan K; Sarchet, Kara N; Hinds, Daniel M; Kamendulis, Lisa M; Hingtgen, Cynthia M; Case, Jamie; Clapp, D Wade; Conway, Simon J; Stansfield, Brian K; Ingram, David A.

Afiliación

Li F; Department of Pediatrics (F.L., B.D.D., L.C.S., J.A.M., M.R.D., W.K.B., K.N.S., D.M.H., J.C., D.W.C., S.J.C., B.K.S., D.A.I.), Wells Center for Pediatric Research (F.L., B.D.D., L.C.S., J.A.M., M.R.D., W.K.B., K.N.S., D.M.H., J.C., D.W.C., S.J.C., B.K.S., D.A.I.), Department of Biochemistry and Molecular Biology (B.D.D., D.W.C., S.J.C., D.A.I.), Microbiology and Immunology (M.R.D.), Pharmacology and Toxicology (L.M.K.), and Neurology (C.M.H.), Indiana University School of Medicine, Indianapolis,

Circulation ; 129(11): 1213-24, 2014 Mar 18.

Article en En | MEDLINE | ID: mdl-24370551

Asunto(s)

Aneurisma/metabolismo; Células Mieloides/metabolismo; Neurofibromina 1/deficiencia; Aneurisma/tratamiento farmacológico; Aneurisma/genética; Animales; Masculino; Ratones; Ratones de la Cepa 129; Ratones Endogámicos C57BL; Ratones Transgénicos; Neurofibromina 1/genética; Simvastatina/uso terapéutico

Palabras clave

Hydroxymethylglutaryl-CoA reductase inhibitors; aneurysm; antioxidants; genetics; inflammation; leukocytes; mice, transgenic

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Células Mieloides / Neurofibromina 1 / Aneurisma Idioma: En Revista: Circulation Año: 2014 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google