Interleukin 10 receptor signaling: master regulator of intestinal mucosal homeostasis in mice and humans.

Shouval, Dror S; Ouahed, Jodie; Biswas, Amlan; Goettel, Jeremy A; Horwitz, Bruce H; Klein, Christoph; Muise, Aleixo M; Snapper, Scott B

Shouval, Dror S; Ouahed, Jodie; Biswas, Amlan; Goettel, Jeremy A; Horwitz, Bruce H; Klein, Christoph; Muise, Aleixo M; Snapper, Scott B.

Afiliación

Shouval DS; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Ouahed J; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Biswas A; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Goettel JA; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Horwitz BH; Division of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.
Klein C; Dr von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany.
Muise AM; Division of Gastroenterology, Hepatology, and Nutrition, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada; Program in Cell Biology at University of Toronto, Toronto, Ontario, Canada.
Snapper SB; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Division of Gastroenterology, Brigham & Women's Hospital, Boston, Massachusetts, USA. Electronic address: scott.snapper@childrens.harvard.edu.

Adv Immunol ; 122: 177-210, 2014.

Article en En | MEDLINE | ID: mdl-24507158

Asunto(s)

Homeostasis/inmunología; Enfermedades Inflamatorias del Intestino/inmunología; Mucosa Intestinal/inmunología; Receptores de Interleucina-10/fisiología; Transducción de Señal/inmunología; Inmunidad Adaptativa/genética; Animales; Enterocolitis/inmunología; Enterocolitis/metabolismo; Enterocolitis/patología; Homeostasis/genética; Humanos; Inmunidad Innata/genética; Enfermedades Inflamatorias del Intestino/metabolismo; Enfermedades Inflamatorias del Intestino/patología; Mucosa Intestinal/metabolismo; Mucosa Intestinal/patología; Ratones; Receptores de Interleucina-10/deficiencia; Transducción de Señal/genética

Palabras clave

Colitis; IBD; IL10; IL10 receptor; Microbiome; Very early-onset IBD

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Enfermedades Inflamatorias del Intestino / Transducción de Señal / Receptores de Interleucina-10 / Homeostasis / Mucosa Intestinal Idioma: En Revista: Adv Immunol Año: 2014 Tipo del documento: Article

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