Sudden hearing loss followed by deep vein thrombosis and pulmonary embolism in a patient with factor V Leiden mutation.
Int J Audiol
; 53(9): 625-8, 2014 Sep.
Article
en En
| MEDLINE
| ID: mdl-24735015
ABSTRACT
OBJECTIVE:
Factor V Leiden (FVL) is by far the most prevalent inherited thrombophilic abnormality in Western countries, and this genetic condition has been associated with sudden sensorineural hearing loss (SSHL). Audiologists should be aware that SSHL may be the precursor of life-threatening thromboembolic events, especially in Caucasians who are more likely to be FVL carriers.DESIGN:
Case report. STUDY SAMPLE A 41-year-old male patient.RESULTS:
Although this is not the first report of SSHL in a FVL carrier, it is the first to describe SSHL occurring in a heterozygous FVL carrier who--within a month--was also diagnosed with deep vein thrombosis of the left common femoral, saphenous, and popliteal veins, and pulmonary embolism of the left pulmonary artery branch serving the posterior basal segment of the inferior lobe.CONCLUSIONS:
SSHL is an emergency condition that warrants prompt medical examination and treatment. Hematological investigations should be considered in SSHL patients at least for those with a family history of thrombotic events, and for women on estrogen-progestin therapy or during pregnancy, with a view to providing adequate antithrombotic prophylaxis and reducing the risk of other thromboembolic events.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Embolia Pulmonar
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Factor V
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Trombosis de la Vena
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Resistencia a la Proteína C Activada
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Pérdida Auditiva Súbita
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Pérdida Auditiva Sensorineural
/
Mutación
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Int J Audiol
Asunto de la revista:
AUDIOLOGIA
Año:
2014
Tipo del documento:
Article