Error-free versus mutagenic processing of genomic uracil--relevance to cancer.

Krokan, Hans E; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik Sahlin; Kavli, Bodil; Slupphaug, Geir

Krokan, Hans E; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik Sahlin; Kavli, Bodil; Slupphaug, Geir.

Afiliación

Krokan HE; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway. Electronic address: hans.krokan@ntnu.no.
Sætrom P; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway; Department of Computer and Information Science, Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.
Aas PA; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway.
Pettersen HS; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway; St. Olav's Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.
Kavli B; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway.
Slupphaug G; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway.

DNA Repair (Amst) ; 19: 38-47, 2014 Jul.

Article en En | MEDLINE | ID: mdl-24746924

Asunto(s)

Reparación del ADN/genética; Linfoma de Células B/genética; Mutagénesis; Uracilo/metabolismo; Desaminasas APOBEC-1; Inmunidad Adaptativa/genética; Animales; Citidina Desaminasa/genética; Citidina Desaminasa/metabolismo; Citosina/metabolismo; ADN Glicosilasas/genética; ADN Glicosilasas/metabolismo; Humanos; Linfoma de Células B/metabolismo; Linfoma de Células B/patología; Proteínas Nucleares/genética; Proteínas Nucleares/metabolismo; Nucleotidiltransferasas/genética; Nucleotidiltransferasas/metabolismo

Palabras clave

AID/APOBEC; Adaptive immunity; Base excision repair; Cancer; Genomic uracil; Mutational signatures

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Uracilo / Linfoma de Células B / Mutagénesis / Reparación del ADN Idioma: En Revista: DNA Repair (Amst) Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 2014 Tipo del documento: Article

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