Tumor necrosis factor (TNF)-&#945; induction of CXCL10 in endothelial cells requires protein arginine methyltransferase 5 (PRMT5)-mediated nuclear factor (NF)-&#954;B p65 methylation.

Harris, Daniel P; Bandyopadhyay, Smarajit; Maxwell, Tyler J; Willard, Belinda; DiCorleto, Paul E

Tumor necrosis factor (TNF)-α induction of CXCL10 in endothelial cells requires protein arginine methyltransferase 5 (PRMT5)-mediated nuclear factor (NF)-κB p65 methylation.

Harris, Daniel P; Bandyopadhyay, Smarajit; Maxwell, Tyler J; Willard, Belinda; DiCorleto, Paul E.

Afiliación

Harris DP; From the Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44195 and Department of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Bandyopadhyay S; From the Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44195 and.
Maxwell TJ; From the Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44195 and.
Willard B; From the Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44195 and.
DiCorleto PE; From the Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44195 and Department of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106 dicorlp@ccf.org.

J Biol Chem ; 289(22): 15328-39, 2014 May 30.

Article en En | MEDLINE | ID: mdl-24753255

Asunto(s)

Quimiocina CXCL10/genética; Células Endoteliales/fisiología; Proteína-Arginina N-Metiltransferasas/metabolismo; Factor de Transcripción ReIA/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo; Arginina/metabolismo; Quimiocina CXCL10/metabolismo; Células Endoteliales/citología; Humanos; Inflamación/genética; Inflamación/metabolismo; Metilación; Cultivo Primario de Células; Regiones Promotoras Genéticas/fisiología; Procesamiento Proteico-Postraduccional/fisiología; Proteína-Arginina N-Metiltransferasas/genética; Transcripción Genética/fisiología

Palabras clave

Endothelial Cell; Gene Expression; NF-Kappa B (NF-KB); Post-Translational Modification (PTM); Protein Methylation; Tumor Necrosis Factor (TNF)

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteína-Arginina N-Metiltransferasas / Factor de Necrosis Tumoral alfa / Células Endoteliales / Factor de Transcripción ReIA / Quimiocina CXCL10 Tipo de estudio: Prognostic_studies Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article

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