Citral: a monoterpene with prophylactic and therapeutic anti-nociceptive effects in experimental models of acute and chronic pain.

Nishijima, Catarine M; Ganev, Ellen G; Mazzardo-Martins, Leidiane; Martins, Daniel F; Rocha, Lúcia R M; Santos, Adair R S; Hiruma-Lima, Clelia A

Nishijima, Catarine M; Ganev, Ellen G; Mazzardo-Martins, Leidiane; Martins, Daniel F; Rocha, Lúcia R M; Santos, Adair R S; Hiruma-Lima, Clelia A.

Afiliación

Nishijima CM; Natural Products Laboratory, Department of Physiology, Bioscience Institute, Universidade Estadual Paulista 'Júlio de Mesquita Filho', Botucatu, São Paulo 18618-970, Brazil. Electronic address: cat.nishi@ig.com.br.
Ganev EG; Natural Products Laboratory, Department of Physiology, Bioscience Institute, Universidade Estadual Paulista 'Júlio de Mesquita Filho', Botucatu, São Paulo 18618-970, Brazil. Electronic address: ellen_gg@yahoo.com.br.
Mazzardo-Martins L; Laboratory of Neurobiology of Pain and Inflammation, Department of Physiological Sciences, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Santa Catarina, Brazil. Electronic address: leidiane2001@yahoo.com.br.
Martins DF; Laboratory of Neurobiology of Pain and Inflammation, Department of Physiological Sciences, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Santa Catarina, Brazil. Electronic address: danielmartinsfisio@hotmail.com.
Rocha LR; Natural Products Laboratory, Department of Physiology, Bioscience Institute, Universidade Estadual Paulista 'Júlio de Mesquita Filho', Botucatu, São Paulo 18618-970, Brazil. Electronic address: lrocha@ibb.unesp.br.
Santos AR; Laboratory of Neurobiology of Pain and Inflammation, Department of Physiological Sciences, Centre of Biological Sciences, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Santa Catarina, Brazil. Electronic address: adair.santos@ufsc.br.
Hiruma-Lima CA; Natural Products Laboratory, Department of Physiology, Bioscience Institute, Universidade Estadual Paulista 'Júlio de Mesquita Filho', Botucatu, São Paulo 18618-970, Brazil. Electronic address: hiruma@ibb.unesp.br.

Eur J Pharmacol ; 736: 16-25, 2014 Aug 05.

Article en En | MEDLINE | ID: mdl-24792822

Asunto(s)

Dolor Agudo/tratamiento farmacológico; Analgésicos/uso terapéutico; Dolor Crónico/tratamiento farmacológico; Monoterpenos/uso terapéutico; Receptor de Serotonina 5-HT2A/metabolismo; Dolor Agudo/inducido químicamente; Dolor Agudo/metabolismo; Monoterpenos Acíclicos; Analgésicos/farmacología; Animales; Capsaicina; Dolor Crónico/etiología; Dolor Crónico/metabolismo; Aminoácidos Excitadores; Formaldehído; Ácido Glutámico; Hiperalgesia/tratamiento farmacológico; Hiperalgesia/metabolismo; Isquemia/complicaciones; Ketanserina/farmacología; Masculino; Ratones; Monoterpenos/farmacología; Neuralgia/tratamiento farmacológico; Neuralgia/metabolismo; Dolor Postoperatorio/tratamiento farmacológico; Dolor Postoperatorio/metabolismo; Ratas Wistar; Antagonistas del Receptor de Serotonina 5-HT2/farmacología; Úlcera Gástrica/tratamiento farmacológico; Úlcera Gástrica/metabolismo; Sustancia P; Acetato de Tetradecanoilforbol; Factor de Necrosis Tumoral alfa

Palabras clave

Chronic pain; Chronic regional pain syndrome; Citral; Gastro-protective effect; Neuropathic pain; Postoperative pain

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Monoterpenos / Receptor de Serotonina 5-HT2A / Dolor Agudo / Dolor Crónico / Analgésicos Tipo de estudio: Etiology_studies / Prognostic_studies Idioma: En Revista: Eur J Pharmacol Año: 2014 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google