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Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography.
Orth, Peter; Xiao, Li; Hernandez, Lorraine D; Reichert, Paul; Sheth, Payal R; Beaumont, Maribel; Yang, Xiaoyu; Murgolo, Nicholas; Ermakov, Grigori; DiNunzio, Edward; Racine, Fred; Karczewski, Jerzy; Secore, Susan; Ingram, Richard N; Mayhood, Todd; Strickland, Corey; Therien, Alex G.
Afiliación
  • Orth P; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Xiao L; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Hernandez LD; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Reichert P; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Sheth PR; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Beaumont M; Merck & Co., Inc., Palo Alto, California 94304, and.
  • Yang X; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Murgolo N; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Ermakov G; Merck & Co., Inc., Palo Alto, California 94304, and.
  • DiNunzio E; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Racine F; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Karczewski J; Merck & Co., Inc., West Point, Pennsylvania 19486.
  • Secore S; Merck & Co., Inc., West Point, Pennsylvania 19486.
  • Ingram RN; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Mayhood T; From Merck & Co., Inc., Kenilworth, New Jersey 07023.
  • Strickland C; From Merck & Co., Inc., Kenilworth, New Jersey 07023, corey.strickland@merck.com.
  • Therien AG; From Merck & Co., Inc., Kenilworth, New Jersey 07023, alex_therien@merck.com.
J Biol Chem ; 289(26): 18008-21, 2014 Jun 27.
Article en En | MEDLINE | ID: mdl-24821719
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Toxinas Bacterianas / Clostridioides difficile / Anticuerpos Neutralizantes / Anticuerpos Antibacterianos / Epítopos Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Bacterianas / Toxinas Bacterianas / Clostridioides difficile / Anticuerpos Neutralizantes / Anticuerpos Antibacterianos / Epítopos Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article