Emergence of Multidrug Resistant Extended-Spectrum ß-Lactamase Producing Eshcherichia coli Associated With Urinary Tract Infections in Bangladesh.
J Basic Clin Pharm
; 3(1): 225-8, 2011 Dec.
Article
en En
| MEDLINE
| ID: mdl-24826028
ABSTRACT
The incidence of infections due to extended-spectrum ß-lactamase (ESBL)-producing Escherichia coli has been increased dramatically in recent years. Treatment is difficult because of frequent multidrug resistance. To identify the sensitivity of commonly used antibiotics, 36 ESBL producing E. coli strains were isolated from young adult female patients in a govt. medical college hospital in Bangladesh. The samples were studied for antimicrobial sensitivity against nine (9) commonly used antibiotics namely ampicillin (amp), trimethoprim-sulfomethoxazole (tms), tetracycline (tet), ciprofloxacin (cip), mecillinum (mel), ceftriaxone (cef), nalidixic acid (nal), Azithromycin (azm) and Chloramphenicol (chl) and the MIC values were determined by agar dilution method. Overall, 72% of the strains were multidrug resistant (MDR) i.e. resistant to two or more drugs. Among 36 strains, 14 isolates were initially found to be resistant against third generation cephalosporin, ceftriaxone. Those were subjected to the test for production of ESBL (Extended Spectrum ß-Lactamase) and 7 showed positive results.
Texto completo:
1
Base de datos:
MEDLINE
Tipo de estudio:
Risk_factors_studies
Idioma:
En
Revista:
J Basic Clin Pharm
Año:
2011
Tipo del documento:
Article