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Spontaneous CNV in a novel mutant mouse is associated with early VEGF-A-driven angiogenesis and late-stage focal edema, neural cell loss, and dysfunction.
Nagai, Norihiro; Lundh von Leithner, Pete; Izumi-Nagai, Kanako; Hosking, Brett; Chang, Bo; Hurd, Ron; Adamson, Peter; Adamis, Anthony P; Foxton, Richard H; Ng, Yin Shan; Shima, David T.
Afiliación
  • Nagai N; Department of Ocular Biology and Therapeutics, University College London, Institute of Ophthalmology, London, United Kingdom.
  • Lundh von Leithner P; Department of Ocular Biology and Therapeutics, University College London, Institute of Ophthalmology, London, United Kingdom.
  • Izumi-Nagai K; Department of Ocular Biology and Therapeutics, University College London, Institute of Ophthalmology, London, United Kingdom.
  • Hosking B; Department of Ocular Biology and Therapeutics, University College London, Institute of Ophthalmology, London, United Kingdom.
  • Chang B; The Jackson Laboratory, Bar Harbor, Maine, United States.
  • Hurd R; The Jackson Laboratory, Bar Harbor, Maine, United States.
  • Adamson P; GSK Ophthalmology, GlaxoSmithKline, Stevenage, Hertfordshire, United Kingdom.
  • Adamis AP; Genentech, Inc., South San Francisco, California, United States.
  • Foxton RH; Department of Ocular Biology and Therapeutics, University College London, Institute of Ophthalmology, London, United Kingdom.
  • Ng YS; Department of Ocular Biology and Therapeutics, University College London, Institute of Ophthalmology, London, United Kingdom.
  • Shima DT; Department of Ocular Biology and Therapeutics, University College London, Institute of Ophthalmology, London, United Kingdom.
Invest Ophthalmol Vis Sci ; 55(6): 3709-19, 2014 May 20.
Article en En | MEDLINE | ID: mdl-24845632
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Coroides / Neovascularización Coroidal / Factor A de Crecimiento Endotelial Vascular / Edema / Epitelio Pigmentado de la Retina Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Invest Ophthalmol Vis Sci Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Coroides / Neovascularización Coroidal / Factor A de Crecimiento Endotelial Vascular / Edema / Epitelio Pigmentado de la Retina Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Invest Ophthalmol Vis Sci Año: 2014 Tipo del documento: Article