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A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determination.
Rudolf, Amalie Frederikke; Skovgaard, Tine; Knapp, Stefan; Jensen, Lars Juhl; Berthelsen, Jens.
Afiliación
  • Rudolf AF; Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Skovgaard T; Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Knapp S; Structural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
  • Jensen LJ; Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Berthelsen J; Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark; Costerton Biofilm Center, Institute for International Health, Immunology and Microbiology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
PLoS One ; 9(6): e98800, 2014.
Article en En | MEDLINE | ID: mdl-24915177
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Quinasas / Inhibidores de Proteínas Quinasas / Evaluación Preclínica de Medicamentos Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Quinasas / Inhibidores de Proteínas Quinasas / Evaluación Preclínica de Medicamentos Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2014 Tipo del documento: Article