Metabolic syndrome impairs notch signaling and promotes apoptosis in chronically ischemic myocardium.

Elmadhun, Nassrene Y; Sabe, Ashraf A; Lassaletta, Antonio D; Chu, Louis M; Kondra, Katelyn; Sturek, Michael; Sellke, Frank W

Elmadhun, Nassrene Y; Sabe, Ashraf A; Lassaletta, Antonio D; Chu, Louis M; Kondra, Katelyn; Sturek, Michael; Sellke, Frank W.

Afiliación

Elmadhun NY; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Brown University Warren Alpert School of Medicine, Providence, RI.
Sabe AA; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Brown University Warren Alpert School of Medicine, Providence, RI.
Lassaletta AD; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Brown University Warren Alpert School of Medicine, Providence, RI.
Chu LM; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Brown University Warren Alpert School of Medicine, Providence, RI.
Kondra K; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Brown University Warren Alpert School of Medicine, Providence, RI.
Sturek M; Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Ind.
Sellke FW; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Brown University Warren Alpert School of Medicine, Providence, RI. Electronic address: fsellke@lifespan.org.

J Thorac Cardiovasc Surg ; 148(3): 1048-55; discussion 1055, 2014 Sep.

Article en En | MEDLINE | ID: mdl-25037620

Asunto(s)

Apoptosis; Síndrome Metabólico/complicaciones; Isquemia Miocárdica/complicaciones; Miocardio/metabolismo; Receptores Notch/metabolismo; Transducción de Señal; Proteínas Angiogénicas/metabolismo; Animales; Proteínas Reguladoras de la Apoptosis/metabolismo; Enfermedad Crónica; Modelos Animales de Enfermedad; Masculino; Síndrome Metabólico/metabolismo; Síndrome Metabólico/patología; Síndrome Metabólico/fisiopatología; Isquemia Miocárdica/metabolismo; Isquemia Miocárdica/patología; Isquemia Miocárdica/fisiopatología; Miocardio/patología; Neovascularización Fisiológica; Porcinos; Porcinos Enanos; Factores de Tiempo

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Transducción de Señal / Isquemia Miocárdica / Apoptosis / Síndrome Metabólico / Receptores Notch / Miocardio Tipo de estudio: Prognostic_studies Idioma: En Revista: J Thorac Cardiovasc Surg Año: 2014 Tipo del documento: Article

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