In vivo anti-diabetic, antioxidant and molecular docking studies of 1, 2, 8-trihydroxy-6-methoxy xanthone and 1, 2-dihydroxy-6-methoxyxanthone-8-O-ß-D-xylopyranosyl isolated from Swertia corymbosa.

Mahendran, G; Manoj, M; Murugesh, E; Sathish Kumar, R; Shanmughavel, P; Rajendra Prasad, K J; Narmatha Bai, V

Mahendran, G; Manoj, M; Murugesh, E; Sathish Kumar, R; Shanmughavel, P; Rajendra Prasad, K J; Narmatha Bai, V.

Afiliación

Mahendran G; Plant Tissue Culture Laboratory, Department of Botany, School of Life Sciences, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India. Electronic address: mahendran0007@gmail.com.
Manoj M; Department of Chemistry, School of Chemical Sciences, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Murugesh E; Computational Biology Lab, Bioinformatics Department, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Sathish Kumar R; Computational Biology Lab, Bioinformatics Department, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Shanmughavel P; Computational Biology Lab, Bioinformatics Department, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Rajendra Prasad KJ; Department of Chemistry, School of Chemical Sciences, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Narmatha Bai V; Plant Tissue Culture Laboratory, Department of Botany, School of Life Sciences, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.

Phytomedicine ; 21(11): 1237-48, 2014 Sep 25.

Article en En | MEDLINE | ID: mdl-25172785

Asunto(s)

Diabetes Mellitus Experimental/tratamiento farmacológico; Hipoglucemiantes/farmacología; Hipolipemiantes/farmacología; Extractos Vegetales/farmacología; Swertia/química; Animales; Prueba de Tolerancia a la Glucosa; Riñón/enzimología; Riñón/patología; Hígado/enzimología; Hígado/patología; Masculino; Ratones; Simulación del Acoplamiento Molecular; Fitoterapia; Componentes Aéreos de las Plantas/química; Ratas Wistar; Pruebas de Toxicidad Aguda; Xantonas/farmacología

Palabras clave

2BEL; Antidiabetic activity; Antioxidant; SUR1; Swertia corymbosa; Xanthones

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Swertia / Diabetes Mellitus Experimental / Hipoglucemiantes / Hipolipemiantes Idioma: En Revista: Phytomedicine Asunto de la revista: TERAPIAS COMPLEMENTARES Año: 2014 Tipo del documento: Article

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