Differential effects of atorvastatin on autophagy in ischemic and nonischemic myocardium in Ossabaw swine with metabolic syndrome.

Sabe, Ashraf A; Elmadhun, Nassrene Y; Sadek, Ahmed A; Chu, Louis M; Bianchi, Cesario; Sellke, Frank W

Sabe, Ashraf A; Elmadhun, Nassrene Y; Sadek, Ahmed A; Chu, Louis M; Bianchi, Cesario; Sellke, Frank W.

Afiliación

Sabe AA; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Warren Alpert School of Medicine, Brown University, Providence, RI.
Elmadhun NY; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Warren Alpert School of Medicine, Brown University, Providence, RI.
Sadek AA; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Warren Alpert School of Medicine, Brown University, Providence, RI.
Chu LM; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Warren Alpert School of Medicine, Brown University, Providence, RI.
Bianchi C; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Warren Alpert School of Medicine, Brown University, Providence, RI.
Sellke FW; Division of Cardiothoracic Surgery, Cardiovascular Research Center, Warren Alpert School of Medicine, Brown University, Providence, RI. Electronic address: fsellke@lifespan.org.

J Thorac Cardiovasc Surg ; 148(6): 3172-8, 2014 Dec.

Article en En | MEDLINE | ID: mdl-25240527

Asunto(s)

Autofagia/efectos de los fármacos; Ácidos Heptanoicos/farmacología; Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico; Síndrome Metabólico/tratamiento farmacológico; Isquemia Miocárdica/tratamiento farmacológico; Miocardio/patología; Pirroles/farmacología; Animales; Atorvastatina; Biomarcadores/metabolismo; Colesterol en la Dieta; Modelos Animales de Enfermedad; Masculino; Síndrome Metabólico/diagnóstico; Síndrome Metabólico/metabolismo; Isquemia Miocárdica/diagnóstico; Isquemia Miocárdica/metabolismo; Miocardio/metabolismo; Transducción de Señal/efectos de los fármacos; Porcinos

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirroles / Autofagia / Isquemia Miocárdica / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Síndrome Metabólico / Ácidos Heptanoicos / Miocardio Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: J Thorac Cardiovasc Surg Año: 2014 Tipo del documento: Article

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