Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome: a historical perspective.
Gene
; 555(1): 33-40, 2015 Jan 15.
Article
en En
| MEDLINE
| ID: mdl-25260227
ABSTRACT
Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a congenital defect of the Müllerian ducts characterized by uterovaginal agenesis and underdeveloped female genital organs. This paper is a tribute to the contributors of this condition - August Franz Joseph Karl Mayer, Karl Freiherr von Rokitansky, Hermann Küster and Georges André Hauser. In addition to their contributions, we have discussed findings and reports of similar defects from other important scientists (Hippocrates, Albucasis, etc.) dating as far back as 460B.C. We have also discussed the disease types and different classification systems including VCUAM and AFS/ASRM among others. Even with several surgical and non-surgical treatment options, there are still many questions that remain unanswered and very little is known about the etiology or genetic predisposition of this condition.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Anomalías Congénitas
/
Trastornos del Desarrollo Sexual 46, XX
/
Conductos Paramesonéfricos
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Gene
Año:
2015
Tipo del documento:
Article