A short sequence motif in the 5' leader of the HIV-1 genome modulates extended RNA dimer formation and virus replication.

van Bel, Nikki; Das, Atze T; Cornelissen, Marion; Abbink, Truus E M; Berkhout, Ben

van Bel, Nikki; Das, Atze T; Cornelissen, Marion; Abbink, Truus E M; Berkhout, Ben.

Afiliación

van Bel N; From the Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam, Academic Medical Centre Amsterdam, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands and.
Das AT; From the Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam, Academic Medical Centre Amsterdam, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands and.
Cornelissen M; From the Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam, Academic Medical Centre Amsterdam, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands and.
Abbink TE; From the Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam, Academic Medical Centre Amsterdam, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands and the Department of Medicine, Addenbrooke's Hospital, Cambridge CB2 0SP, Uni
Berkhout B; From the Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam, Academic Medical Centre Amsterdam, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands and B.Berkhout@amc.uva.nl.

J Biol Chem ; 289(51): 35061-74, 2014 Dec 19.

Article en En | MEDLINE | ID: mdl-25368321

Asunto(s)

Genoma Viral/genética; VIH-1/genética; Motivos de Nucleótidos/genética; ARN Viral/genética; Replicación Viral/genética; Emparejamiento Base; Secuencia de Bases; Northern Blotting; Línea Celular Tumoral; Dimerización; Células HEK293; VIH-1/química; VIH-1/metabolismo; Humanos; Modelos Moleculares; Mutación; Conformación de Ácido Nucleico; ARN Viral/química; ARN Viral/metabolismo; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Linfocitos T/patología; Linfocitos T/virología; Transcripción Genética

Palabras clave

HIV-1 Protease; HIV-1 RNA; HIV-1 RNA Packaging; Molecular Evolution; RNA Dimerization; RNA Structure; Reverse Transcription; Virology; Virus Evolution

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Replicación Viral / ARN Viral / VIH-1 / Genoma Viral / Motivos de Nucleótidos Tipo de estudio: Prognostic_studies Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article

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