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A new prenylated indole diketopiperazine alkaloid from Eurotium cristatum.
Zou, Xianwei; Li, Ying; Zhang, Xiaona; Li, Qian; Liu, Xuan; Huang, Yun; Tang, Tao; Zheng, Saijing; Wang, Weimiao; Tang, Jintian.
Afiliación
  • Zou X; Key Laboratory of Particle & Radiation Imaging, Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing 100084, China. zouxw000@126.com.
  • Li Y; Key Laboratory of Particle & Radiation Imaging, Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing 100084, China. liying_90126@126.com.
  • Zhang X; Key Laboratory of Particle & Radiation Imaging, Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing 100084, China. zouxw000@126.com.
  • Li Q; Key Laboratory of Particle & Radiation Imaging, Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing 100084, China. yaoyaoldlq@163.com.
  • Liu X; Key Laboratory of Particle & Radiation Imaging, Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing 100084, China. liux_54@163.com.
  • Huang Y; Key Laboratory of Particle & Radiation Imaging, Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing 100084, China. sungood591@sina.com.
  • Tang T; Key Laboratory of Particle & Radiation Imaging, Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing 100084, China. tao_tang1@126.com.
  • Zheng S; Shanghai Tobacco Group Corporation, Shanghai 200082, China. zhengsj@sh.tobacco.com.cn.
  • Wang W; Shanghai Tobacco Group Corporation, Shanghai 200082, China. zdsys@sh.tobacco.com.cn.
  • Tang J; Key Laboratory of Particle & Radiation Imaging, Ministry of Education, Department of Engineering Physics, Tsinghua University, Beijing 100084, China. tangjt@mail.tsinghua.edu.cn.
Molecules ; 19(11): 17839-47, 2014 Nov 03.
Article en En | MEDLINE | ID: mdl-25372398
ABSTRACT
A new prenylated indole diketopiperazine alkaloid, cristatumin F (1), and four known metabolites, echinulin (2), dehydroechinulin (3), neoechinulin A (4) and variecolorin O (5), were isolated from the crude extract of the fungus Eurotium cristatum. The structure of 1 was elucidated primarily by NMR and MS methods. The absolute configuration of 1 was assigned using Marfey's method applied to its acid hydrolyzate. Cristatumin F (1) showed modest radical scavenging activity against DPPH radicals, and exhibited marginal attenuation of 3T3L1 pre-adipocytes.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Alcaloides / Dicetopiperazinas / Eurotium / Indoles Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2014 Tipo del documento: Article
Texto completo
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XML
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Alcaloides / Dicetopiperazinas / Eurotium / Indoles Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2014 Tipo del documento: Article