Dihydroxanthenones from the fermentation product of an endophytic fungus Gliomastix murorum.
J Asian Nat Prod Res
; 17(4): 319-23, 2015.
Article
en En
| MEDLINE
| ID: mdl-25391819
ABSTRACT
Three new dihydroxanthones, muroxanthenones A-C (1-3), together with three known dihydroxanthones (4-6) were isolated from the fermentation products of an endophytic fungus Gliomastix murorum. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compound 3 showed high cytotoxicities against NB4 and PC3 cell with IC(50) values of 2.2 and 2.8 µM. The other compounds also showed moderate cytotoxicities for some tested cell lines with IC(50) values between 4.1 and 9.5 µM.
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Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Xantonas
/
Hypocreales
/
Antineoplásicos
Idioma:
En
Revista:
J Asian Nat Prod Res
Asunto de la revista:
BOTANICA
/
QUIMICA
Año:
2015
Tipo del documento:
Article