Community resources and technologies developed through the NIH Roadmap Epigenomics Program.
Methods Mol Biol
; 1238: 27-49, 2015.
Article
en En
| MEDLINE
| ID: mdl-25421653
ABSTRACT
This chapter describes resources and technologies generated by the NIH Roadmap Epigenomics Program that may be useful to epigenomics researchers investigating a variety of diseases including cancer. Highlights include reference epigenome maps for a wide variety of human cells and tissues, the development of new technologies for epigenetic assays and imaging, the identification of novel epigenetic modifications, and an improved understanding of the role of epigenetic processes in a diversity of human diseases. We also discuss future needs in this area including exploration of epigenomic variation between individuals, single-cell epigenomics, environmental epigenomics, exploration of the use of surrogate tissues, and improved technologies for epigenome manipulation.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Técnicas Genéticas
/
Epigenómica
/
National Institutes of Health (U.S.)
Tipo de estudio:
Prognostic_studies
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Methods Mol Biol
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2015
Tipo del documento:
Article