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Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells.
Bell, Charles J M; Sun, Yongliang; Nowak, Urszula M; Clark, Jan; Howlett, Sarah; Pekalski, Marcin L; Yang, Xin; Ast, Oliver; Waldhauer, Inja; Freimoser-Grundschober, Anne; Moessner, Ekkehard; Umana, Pablo; Klein, Christian; Hosse, Ralf J; Wicker, Linda S; Peterson, Laurence B.
Afiliación
  • Bell CJ; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge CB2 OXY, United Kingdom. Electronic address: charlie.bell@cimr.cam.ac.uk.
  • Sun Y; Former Roche Site of Pharmaceutical Research and Early Development, Discovery Inflammation, Nutley, NJ 07110, USA. Electronic address: yongliang.sun@pfizer.com.
  • Nowak UM; Former Roche Site of Pharmaceutical Research and Early Development, Discovery Inflammation, Nutley, NJ 07110, USA. Electronic address: umn2001@med.cornell.edu.
  • Clark J; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge CB2 OXY, United Kingdom. Electronic address: janclark@btinternet.com.
  • Howlett S; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge CB2 OXY, United Kingdom. Electronic address: sarah.howlett@cimr.cam.ac.uk.
  • Pekalski ML; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge CB2 OXY, United Kingdom. Electronic address: marcin.pekalski@cimr.cam.ac.uk.
  • Yang X; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge CB2 OXY, United Kingdom. Electronic address: xin.yang@cimr.cam.ac.uk.
  • Ast O; Roche Pharmaceutical Research and Early Development, Large Molecule Research, Roche Innovation Center Zurich, Wagistrasse 18, CH-8952 Schlieren, Switzerland. Electronic address: oliver.ast@roche.com.
  • Waldhauer I; Roche Pharmaceutical Research and Early Development, Oncology Discovery & Translational Area, Roche Innovation Center Zurich, Wagistrasse 18, CH-8952 Schlieren, Switzerland. Electronic address: inja.waldhauer@roche.com.
  • Freimoser-Grundschober A; Roche Pharmaceutical Research and Early Development, Large Molecule Research, Roche Innovation Center Zurich, Wagistrasse 18, CH-8952 Schlieren, Switzerland. Electronic address: anne.freimoser-grundschober@roche.com.
  • Moessner E; Roche Pharmaceutical Research and Early Development, Large Molecule Research, Roche Innovation Center Zurich, Wagistrasse 18, CH-8952 Schlieren, Switzerland. Electronic address: ekkehard.moessner@roche.com.
  • Umana P; Roche Pharmaceutical Research and Early Development, Oncology Discovery & Translational Area, Roche Innovation Center Zurich, Wagistrasse 18, CH-8952 Schlieren, Switzerland. Electronic address: pablo.umana@roche.com.
  • Klein C; Roche Pharmaceutical Research and Early Development, Oncology Discovery & Translational Area, Roche Innovation Center Zurich, Wagistrasse 18, CH-8952 Schlieren, Switzerland. Electronic address: christian.klein.ck1@roche.com.
  • Hosse RJ; Roche Pharmaceutical Research and Early Development, Large Molecule Research, Roche Innovation Center Zurich, Wagistrasse 18, CH-8952 Schlieren, Switzerland. Electronic address: ralf.hosse@roche.com.
  • Wicker LS; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge CB2 OXY, United Kingdom. Electronic address: linda.wicker@cimr.cam.ac.uk.
  • Peterson LB; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge CB2 OXY, United Kingdom; Former Roche Site of Pharmaceutical Research and Early Developmen
J Autoimmun ; 56: 66-80, 2015 Jan.
Article en En | MEDLINE | ID: mdl-25457307
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Transducción de Señal / Interleucina-2 / Linfocitos T Reguladores Idioma: En Revista: J Autoimmun Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2015 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Transducción de Señal / Interleucina-2 / Linfocitos T Reguladores Idioma: En Revista: J Autoimmun Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2015 Tipo del documento: Article