Effects of alpha-lipoic acid on spatial learning and memory, oxidative stress, and central cholinergic system in a rat model of vascular dementia.

Zhao, Ran-Ran; Xu, Fei; Xu, Xiao-Chen; Tan, Guo-Jun; Liu, Liang-Min; Wu, Ning; Zhang, Wen-Zhong; Liu, Ji-Xiang

Zhao, Ran-Ran; Xu, Fei; Xu, Xiao-Chen; Tan, Guo-Jun; Liu, Liang-Min; Wu, Ning; Zhang, Wen-Zhong; Liu, Ji-Xiang.

Afiliación

Zhao RR; Department of Emergency, The First Hospital of Handan, Handan, Hebei 056002, PR China; Key Laboratory of Neurology of Hebei Province, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050071, PR China. Electronic address: a34251900@163.com.
Xu F; Department of Neurology, The First Hospital of Handan, Handan, Hebei 056002, PR China.
Xu XC; Department of Neurology, The First Hospital of Handan, Handan, Hebei 056002, PR China.
Tan GJ; Key Laboratory of Neurology of Hebei Province, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050071, PR China.
Liu LM; Department of Neurology, The Traditional Chinese Medicine Hospital of Anyang, Anyang, Henan 455000, PR China.
Wu N; Department of Cardiology, The People's Hospital of Guangxi Zhuang Automous Region, Nanning, Guangxi 530021, PR China.
Zhang WZ; Department of Emergency, The First Hospital of Handan, Handan, Hebei 056002, PR China.
Liu JX; Department of Neurosurgery, The First Hospital of Handan, Handan, Hebei 056002, PR China.

Neurosci Lett ; 587: 113-9, 2015 Feb 05.

Article en En | MEDLINE | ID: mdl-25534501

Asunto(s)

Acetilcolina/metabolismo; Acetilcolinesterasa/metabolismo; Colina O-Acetiltransferasa/metabolismo; Demencia Vascular/metabolismo; Memoria/efectos de los fármacos; Estrés Oxidativo/efectos de los fármacos; Aprendizaje Espacial/efectos de los fármacos; Ácido Tióctico/farmacología; Animales; Estenosis Carotídea/complicaciones; Demencia Vascular/etiología; Demencia Vascular/psicología; Hipocampo/efectos de los fármacos; Hipocampo/metabolismo; Masculino; Ratas Wistar

Palabras clave

Acetylcholine; Bilateral common carotid artery occlusion; Chronic cerebral hypoperfusion; Morris water maze; Oxidative stress

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Acetilcolinesterasa / Demencia Vascular / Acetilcolina / Colina O-Acetiltransferasa / Ácido Tióctico / Estrés Oxidativo / Aprendizaje Espacial / Memoria Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Neurosci Lett Año: 2015 Tipo del documento: Article

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