The important role of ADAM8 in the progression of hepatocellular carcinoma induced by diethylnitrosamine in mice.

Li, S-Q; Wang, D-M; Zhu, S; Ma, Z; Li, R-F; Xu, Z-S; Han, H-M

Li, S-Q; Wang, D-M; Zhu, S; Ma, Z; Li, R-F; Xu, Z-S; Han, H-M.

Afiliación

Li SQ; The Molecular Medicine Key Laboratory of Liver Injury and Repair, Medical College, Henan University of Science and Technology, Luoyang, People's Republic of China sanqiangli2001@163.com.
Wang DM; The Molecular Medicine Key Laboratory of Liver Injury and Repair, Medical College, Henan University of Science and Technology, Luoyang, People's Republic of China.
Zhu S; Department of Microbiology Immunology, College of Basic Medical Sciences, Zhengzhou University, People's Republic of China.
Ma Z; The Molecular Medicine Key Laboratory of Liver Injury and Repair, Medical College, Henan University of Science and Technology, Luoyang, People's Republic of China.
Li RF; The Molecular Medicine Key Laboratory of Liver Injury and Repair, Medical College, Henan University of Science and Technology, Luoyang, People's Republic of China.
Xu ZS; The Molecular Medicine Key Laboratory of Liver Injury and Repair, Medical College, Henan University of Science and Technology, Luoyang, People's Republic of China.
Han HM; The Molecular Medicine Key Laboratory of Liver Injury and Repair, Medical College, Henan University of Science and Technology, Luoyang, People's Republic of China.

Hum Exp Toxicol ; 34(11): 1053-72, 2015 Nov.

Article en En | MEDLINE | ID: mdl-25585999

Asunto(s)

Proteínas ADAM/metabolismo; Antígenos CD/metabolismo; Carcinoma Hepatocelular/metabolismo; Neoplasias Hepáticas/metabolismo; Proteínas de la Membrana/metabolismo; Proteínas ADAM/inmunología; Alanina Transaminasa/sangre; Animales; Anticuerpos Monoclonales/farmacología; Antígenos CD/inmunología; Aspartato Aminotransferasas/sangre; Carcinoma Hepatocelular/patología; Caspasa 3/genética; Caspasa 3/metabolismo; Dietilnitrosamina; Hígado/efectos de los fármacos; Hígado/metabolismo; Hígado/patología; Neoplasias Hepáticas/patología; Masculino; Proteínas de la Membrana/inmunología; Ratones Endogámicos BALB C; Antígeno Nuclear de Célula en Proliferación/genética; Antígeno Nuclear de Célula en Proliferación/metabolismo; Proteínas Proto-Oncogénicas c-bcl-2/genética; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo; Proteína p53 Supresora de Tumor/genética; Proteína p53 Supresora de Tumor/metabolismo; Factor A de Crecimiento Endotelial Vascular/genética; Factor A de Crecimiento Endotelial Vascular/metabolismo; alfa-Fetoproteínas/análisis; Proteína X Asociada a bcl-2/metabolismo

Palabras clave

ADAM8; Bcl2; HCC; P53; monoclonal antibody

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Antígenos CD / Carcinoma Hepatocelular / Proteínas ADAM / Neoplasias Hepáticas / Proteínas de la Membrana Idioma: En Revista: Hum Exp Toxicol Asunto de la revista: TOXICOLOGIA Año: 2015 Tipo del documento: Article

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