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Modification of 3-arylisoquinolines into 3,4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition.
Khadka, Daulat Bikram; Woo, Hyunjung; Yang, Su Hui; Zhao, Chao; Jin, Yifeng; Le, Thanh Nguyen; Kwon, Youngjoo; Cho, Won-Jea.
Afiliación
  • Khadka DB; College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 500-757, Republic of Korea.
  • Woo H; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Global Top 5 Program, Ewha Womans University, Seoul 120-750, Republic of Korea.
  • Yang SH; College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 500-757, Republic of Korea.
  • Zhao C; College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 500-757, Republic of Korea.
  • Jin Y; College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 500-757, Republic of Korea.
  • Le TN; Center for Drug Research and Development, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Caugiay, Hanoi, Vietnam.
  • Kwon Y; College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Global Top 5 Program, Ewha Womans University, Seoul 120-750, Republic of Korea. Electronic address: ykwon@ewha.ac.kr.
  • Cho WJ; College of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 500-757, Republic of Korea. Electronic address: wjcho@chonnam.ac.kr.
Eur J Med Chem ; 92: 583-607, 2015 Mar 06.
Article en En | MEDLINE | ID: mdl-25613224
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Inhibidores de Topoisomerasa I / Isoquinolinas Idioma: En Revista: Eur J Med Chem Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Inhibidores de Topoisomerasa I / Isoquinolinas Idioma: En Revista: Eur J Med Chem Año: 2015 Tipo del documento: Article