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Effects and cost-effectiveness of pharmacogenetic screening for CYP2D6 among older adults starting therapy with nortriptyline or venlafaxine: study protocol for a pragmatic randomized controlled trial (CYSCEtrial).
Berm, Elizabeth J J; Hak, Eelko; Postma, Maarten; Boshuisen, Marjolein; Breuning, Laura; Brouwers, Jacobus R B J; Dhondt, Ton; Jansen, Paul A F; Kok, Rob M; Maring, Jan G; van Marum, Rob; Mulder, Hans; Voshaar, Richard C Oude; Risselada, Arne J; Venema, Harry; Vleugel, Liesbeth; Wilffert, Bob.
Afiliación
  • Berm EJ; Groningen Institute of Pharmacy, University of Groningen, Unit of Pharmacotherapy & Pharmaceutical Care, Antonius Deusinglaan 1, 9713AV, Groningen, The Netherlands. e.j.j.berm@rug.nl.
  • Hak E; Groningen Institute of Pharmacy, University of Groningen, Unit of Pharmacoepidemiology & Pharmacoeconomics, Groningen, The Netherlands. e.hak@rug.nl.
  • Postma M; Department of Epidemiology, University Medical Center Groningen, Groningen, The Netherlands. e.hak@rug.nl.
  • Boshuisen M; Groningen Institute of Pharmacy, University of Groningen, Unit of Pharmacoepidemiology & Pharmacoeconomics, Groningen, The Netherlands. m.j.postma@rug.nl.
  • Breuning L; Department of Epidemiology, University Medical Center Groningen, Groningen, The Netherlands. m.j.postma@rug.nl.
  • Brouwers JR; Lentis, Dignis, Groningen, The Netherlands. m.boshuisen@lentis.nl.
  • Dhondt T; Departement of Old Age and Clinical Psychiatry, Reinier van Arkel Group, 's-Hertogenbosch, The Netherlands. l.breuning@rvagroep.nl.
  • Jansen PA; Groningen Institute of Pharmacy, University of Groningen, Unit of Pharmacotherapy & Pharmaceutical Care, Antonius Deusinglaan 1, 9713AV, Groningen, The Netherlands. jrbjbrouwers@stbebo.nl.
  • Kok RM; Department of Geriatric Medicine and Expertise Centere Pharmacotherapy in Old Persons, UMC Utrecht, Utrecht, The Netherlands. jrbjbrouwers@stbebo.nl.
  • Maring JG; Department of Old-age Psychiatry, GGZ-Noord Holland Noord, Heerhugowaard, The Netherlands. a.dhondt@ggz-nhn.nl.
  • van Marum R; Department of Geriatric Medicine and Expertise Centere Pharmacotherapy in Old Persons, UMC Utrecht, Utrecht, The Netherlands. p.a.f.jansen@umcutrecht.nl.
  • Mulder H; Department of Old Age, Parnassia Psychiatric Institute, The Hague, The Netherlands. r.kok@parnassia.nl.
  • Voshaar RC; Laboratory for Drug Analysis & Toxicology, Diaconessen Hospital Meppel & Bethesda Hospital Hoogeveen, Meppel, The Netherlands. maring@noorderboog.nl.
  • Risselada AJ; Department of Geriatric Medicine, Jeroen Bosch Hospital, 's Hertogenbosch, The Netherlands. r.v.marum@jbz.nl.
  • Venema H; Department of General Practice & Elderly Care Medicine, VU University, Amsterdam, The Netherlands. r.v.marum@jbz.nl.
  • Vleugel L; Clinical Pharmacy, Wilhelmina Hospital Assen, Assen, The Netherlands. hans.mulder@wza.nl.
  • Wilffert B; University of Groningen, University Medical Center Groningen, University Center for Psychiatry, Groningen, The Netherlands. r.c.oude.voshaar@umcg.nl.
Trials ; 16: 37, 2015 Jan 31.
Article en En | MEDLINE | ID: mdl-25636328

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Farmacogenética / Protocolos Clínicos / Citocromo P-450 CYP2D6 / Trastorno Depresivo Mayor / Clorhidrato de Venlafaxina / Antidepresivos / Nortriptilina Tipo de estudio: Clinical_trials / Diagnostic_studies / Guideline / Health_economic_evaluation / Qualitative_research / Screening_studies Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2015 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Farmacogenética / Protocolos Clínicos / Citocromo P-450 CYP2D6 / Trastorno Depresivo Mayor / Clorhidrato de Venlafaxina / Antidepresivos / Nortriptilina Tipo de estudio: Clinical_trials / Diagnostic_studies / Guideline / Health_economic_evaluation / Qualitative_research / Screening_studies Idioma: En Revista: Trials Asunto de la revista: MEDICINA / TERAPEUTICA Año: 2015 Tipo del documento: Article