Simultaneous determination of liensinine, isoliensinine and neferine in rat plasma by UPLC-MS/MS and application of the technique to pharmacokinetic studies.

Hu, Guoxin; Xu, Ren-ai; Dong, Yao-yao; Wang, Yi-yan; Yao, Wen-wen; Chen, Zhi-chuan; Chen, Dongxin; Bu, Tiao; Ge, Ren-shan

Hu, Guoxin; Xu, Ren-ai; Dong, Yao-yao; Wang, Yi-yan; Yao, Wen-wen; Chen, Zhi-chuan; Chen, Dongxin; Bu, Tiao; Ge, Ren-shan.

Afiliación

Hu G; School of Pharmacy, Wenzhou Medical University, Wenzhou 325035, China.
Xu RA; The Second Affiliated Hospital & Yuying Children×³s Hospital of Wenzhou Medical University, Wenzhou 325027, China; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Dong YY; School of Pharmacy, Wenzhou Medical University, Wenzhou 325035, China.
Wang YY; The Second Affiliated Hospital & Yuying Children×³s Hospital of Wenzhou Medical University, Wenzhou 325027, China.
Yao WW; School of Pharmacy, Wenzhou Medical University, Wenzhou 325035, China.
Chen ZC; The Second Affiliated Hospital & Yuying Children×³s Hospital of Wenzhou Medical University, Wenzhou 325027, China.
Chen D; The Second Affiliated Hospital & Yuying Children×³s Hospital of Wenzhou Medical University, Wenzhou 325027, China.
Bu T; The Second Affiliated Hospital & Yuying Children×³s Hospital of Wenzhou Medical University, Wenzhou 325027, China.
Ge RS; The Second Affiliated Hospital & Yuying Children×³s Hospital of Wenzhou Medical University, Wenzhou 325027, China. Electronic address: raygee0828@163.com.

J Ethnopharmacol ; 163: 94-8, 2015 Apr 02.

Article en En | MEDLINE | ID: mdl-25636663

Asunto(s)

Bencilisoquinolinas/sangre; Isoquinolinas/sangre; Fenoles/sangre; Administración Intravenosa; Animales; Bencilisoquinolinas/farmacocinética; Cromatografía Liquida; Isoquinolinas/farmacocinética; Masculino; Fenoles/farmacocinética; Ratas Sprague-Dawley; Espectrometría de Masas en Tándem

Palabras clave

Isoliensinin (PubChem CID: 5274591); Isoliensinine; Liensinine; Liensinine (PubChem CID: 160644); Neferine; Neferine (PubChem CID: 159654); Pharmacokinetics; Rat plasma; UPLCMS/MS

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fenoles / Bencilisoquinolinas / Isoquinolinas Idioma: En Revista: J Ethnopharmacol Año: 2015 Tipo del documento: Article

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