Novel peptide chemistry in terrestrial animals: natural luciferin analogues from the bioluminescent earthworm Fridericia heliota.
Chemistry
; 21(10): 3942-7, 2015 Mar 02.
Article
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| MEDLINE
| ID: mdl-25650756
ABSTRACT
We report isolation and structure elucidation of AsLn5, AsLn7, AsLn11 and AsLn12 novel luciferin analogs from the bioluminescent earthworm Fridericia heliota. They were found to be highly unusual modified peptides, comprising either of the two tyrosine-derived chromophores, CompX or CompY and a set of amino acids, including threonine, gamma-aminobutyric acid, homoarginine, and unsymmetrical N,N-dimethylarginine. These natural compounds represent a unique peptide chemistry found in terrestrial animals and rise novel questions concerning their biosynthetic origin.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Oligoquetos
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Péptidos
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Luciferina de Luciérnaga
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Sustancias Luminiscentes
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Ácido gamma-Aminobutírico
Idioma:
En
Revista:
Chemistry
Asunto de la revista:
QUIMICA
Año:
2015
Tipo del documento:
Article