Assessment of rectocolonic morphology and function in patients with Chagas disease in Barcelona (Spain).
Am J Trop Med Hyg
; 92(5): 898-902, 2015 May.
Article
en En
| MEDLINE
| ID: mdl-25778503
ABSTRACT
The aim of this study was to determine the relationship between colonic symptoms, radiological abnormalities, and anorectal dysfunction in patients with Chagas disease. We performed a cross-sectional study of untreated patients diagnosed with Chagas disease. All patients were evaluated clinically (by a questionnaire for colonic symptoms based on Rome III criteria) and underwent a barium enema and anorectal manometry. A control group of patients with functional constipation and without Chagas disease was included in the study. Overall, 69 patients were included in the study 42 patients were asymptomatic and 27 patients had abdominal symptoms according to Rome III criteria. Anorectal manometry showed a higher proportion of abnormalities in symptomatic patients than in asymptomatic ones (73% versus 21%, respectively; P < 0.0001). Megarectum was detected in a similar proportion in the different subgroups regardless of the presence of symptoms or abnormalities in anorectal functions. Among non-Chagas disease patients with functional constipation, 90% had an abnormal anorectal manometry study. Patients with Chagas disease present a high proportion of constipation with dyssynergic defecation in anorectal manometry but a low prevalence of impaired rectoanal inhibitory reflex, although these abnormalities may be nonspecific for Chagas disease. The presence of megarectum is a nonspecific finding.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Canal Anal
/
Recto
/
Enfermedad de Chagas
/
Estreñimiento
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
País/Región como asunto:
Europa
Idioma:
En
Revista:
Am J Trop Med Hyg
Año:
2015
Tipo del documento:
Article