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Thyroid function is associated with insulin resistance markers in healthy adolescents with risk factors to develop diabetes.
Garduño-Garcia, José de Jesús; Camarillo Romero, Eneida; Loe Ochoa, Ana; Romero-Figueroa, Socorro; Huitron Bravo, Gerardo; Torres García, Roció; Montenegro-Morales, Patricia; Mendieta-Zerón, Hugo.
Afiliación
  • Garduño-Garcia Jde J; Medical Sciences Research Center (CICMED) Cuerpo académico de Salud del Universitario, 50226 Toluca, State of Mexico Mexico ; Coordinación de Investigación en Salud, Delegación México Poniente de Instituto Mexicano del Seguro Social, 50226 Toluca, State of Mexico Mexico.
  • Camarillo Romero E; Medical Sciences Research Center (CICMED) Cuerpo académico de Salud del Universitario, 50226 Toluca, State of Mexico Mexico.
  • Loe Ochoa A; High school Licenciado Adolfo López Mateos, 50226 Toluca, State of Mexico Mexico.
  • Romero-Figueroa S; Coordinación de Investigación en Salud, Delegación México Poniente de Instituto Mexicano del Seguro Social, 50226 Toluca, State of Mexico Mexico.
  • Huitron Bravo G; Medical Sciences Research Center (CICMED) Cuerpo académico de Salud del Universitario, 50226 Toluca, State of Mexico Mexico.
  • Torres García R; Medical Sciences Research Center (CICMED) Cuerpo académico de Salud del Universitario, 50226 Toluca, State of Mexico Mexico.
  • Montenegro-Morales P; Medical Sciences Research Center (CICMED) Cuerpo académico de Salud del Universitario, 50226 Toluca, State of Mexico Mexico.
  • Mendieta-Zerón H; Medical Sciences Research Center (CICMED) Cuerpo académico de biomedicina, 50226 Toluca, State of Mexico Mexico.
Diabetol Metab Syndr ; 7: 16, 2015.
Article en En | MEDLINE | ID: mdl-25780389
INTRODUCTION: The prevalence of obesity and Type 2 diabetes mellitus (T2DM) among children and adolescents is rising. Thyroid function has been associated with insulin resistance. There is scarce information about how thyroid function could be related with cardiovascular risk or glucose homeostasis in adolescent. AIM: To analyze how thyroid function is associated with insulin resistance and another cardiovascular risk factors in healthy adolescents with risk factors to develop diabetes. METHODS: A prospective cross-sectional analysis was carried out on euthyroid, adolescents. considered at high risk to develop Type 2 diabetes. Fasting blood samples were obtained. Thyroid function test and another cardiometabolic parameters were assessed. A 75 grams oral glucose tolerance test was performed to calculate insulin resistance. RESULTS: One hundred adolescents were evaluated. The mean age was 15.9 ± 0.8 years, There is a negative correlation between Fasting insulin, post glucose load insulin and HOMA IR. There were no correlation with Matsuda index. We could not found any correlation with TSH values. CONCLUSIONS: We found a correlation between fasting insulin, HOMA IR and serum thyroid hormones, we did not find any relation with serum TSH. In euthyroid adolescents with risk factors to develop diabetes.
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Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Risk_factors_studies Idioma: En Revista: Diabetol Metab Syndr Año: 2015 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Etiology_studies / Risk_factors_studies Idioma: En Revista: Diabetol Metab Syndr Año: 2015 Tipo del documento: Article