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A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria.
Mbengue, Alassane; Bhattacharjee, Souvik; Pandharkar, Trupti; Liu, Haining; Estiu, Guillermina; Stahelin, Robert V; Rizk, Shahir S; Njimoh, Dieudonne L; Ryan, Yana; Chotivanich, Kesinee; Nguon, Chea; Ghorbal, Mehdi; Lopez-Rubio, Jose-Juan; Pfrender, Michael; Emrich, Scott; Mohandas, Narla; Dondorp, Arjen M; Wiest, Olaf; Haldar, Kasturi.
Afiliación
  • Mbengue A; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA.
  • Bhattacharjee S; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA.
  • Pandharkar T; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA.
  • Liu H; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, USA.
  • Estiu G; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, USA.
  • Stahelin RV; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, USA [3] Department of Biochemistry &Molecular Biology, Indiana University School
  • Rizk SS; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA.
  • Njimoh DL; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA [3] Departmen of. Biochemistry and Molecular Biology, Faculty of Science University of
  • Ryan Y; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA.
  • Chotivanich K; Faculty of Tropical Medicine, Mahidol University, 420/6 Ratchawithi Road, Ratchathewi, Bangkok 10400, Thailand.
  • Nguon C; National Center for Parasitology, Entomology and Malaria Control, 12302 Phnom Penh, Monivong Blvd, Phnom Penh 12302, Cambodia.
  • Ghorbal M; CNRS 5290/IRD 224/University Montpellier 1&2 ("MiVEGEC"), Montpellier, France.
  • Lopez-Rubio JJ; CNRS 5290/IRD 224/University Montpellier 1&2 ("MiVEGEC"), Montpellier, France.
  • Pfrender M; Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA.
  • Emrich S; Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Indiana 46556. USA.
  • Mohandas N; New York Blood Center, New York, New York 10032, USA.
  • Dondorp AM; 1] Faculty of Tropical Medicine, Mahidol University, 420/6 Ratchawithi Road, Ratchathewi, Bangkok 10400, Thailand [2] Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7BN. UK.
  • Wiest O; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, USA [3] Laboratory of Computational Chemistry and Drug Design, Laboratory of Chemica
  • Haldar K; 1] Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, Indiana 46556, USA [2] Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Nature ; 520(7549): 683-7, 2015 Apr 30.
Article en En | MEDLINE | ID: mdl-25874676
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Plasmodium falciparum / Resistencia a Medicamentos / Malaria Falciparum / Artemisininas / Inhibidores de las Quinasa Fosfoinosítidos-3 / Antimaláricos Tipo de estudio: Prognostic_studies Idioma: En Revista: Nature Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Plasmodium falciparum / Resistencia a Medicamentos / Malaria Falciparum / Artemisininas / Inhibidores de las Quinasa Fosfoinosítidos-3 / Antimaláricos Tipo de estudio: Prognostic_studies Idioma: En Revista: Nature Año: 2015 Tipo del documento: Article