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α-Chaconine isolated from a Solanum tuberosum L. cv Jayoung suppresses lipopolysaccharide-induced pro-inflammatory mediators via AP-1 inactivation in RAW 264.7 macrophages and protects mice from endotoxin shock.
Lee, Kyoung-Goo; Lee, Suel-Gie; Lee, Hwi-Ho; Lee, Hae Jun; Shin, Ji-Sun; Kim, Nan-Jung; An, Hyo-Jin; Nam, Jung-Hwan; Jang, Dae Sik; Lee, Kyung-Tae.
Afiliación
  • Lee KG; Department of pharmaceutical Biochemistry, Kyung Hee University, Seoul, Republic of Korea.
  • Lee SG; Department of pharmaceutical Biochemistry, Kyung Hee University, Seoul, Republic of Korea; Department of Life and Nanopharmaceutical Science, Kyung Hee University, Seoul, Republic of Korea.
  • Lee HH; Department of pharmaceutical Biochemistry, Kyung Hee University, Seoul, Republic of Korea; Department of Life and Nanopharmaceutical Science, Kyung Hee University, Seoul, Republic of Korea.
  • Lee HJ; Department of pharmaceutical Biochemistry, Kyung Hee University, Seoul, Republic of Korea; Department of Life and Nanopharmaceutical Science, Kyung Hee University, Seoul, Republic of Korea.
  • Shin JS; Department of pharmaceutical Biochemistry, Kyung Hee University, Seoul, Republic of Korea; Reactive Oxygen Species Medical Research Center, School of Medicine, Kyung Hee University, Republic of Korea.
  • Kim NJ; Department of pharmaceutical Biochemistry, Kyung Hee University, Seoul, Republic of Korea.
  • An HJ; Department of Pharmacology, College of Oriental Medicine, Sangji University, Wonju-si, Gangwon-do 220-702, Republic of Korea.
  • Nam JH; Highland Agriculture Research Center, NICS, RDA, Pyeongchang 232-955, Republic of Korea.
  • Jang DS; Department of Life and Nanopharmaceutical Science, Kyung Hee University, Seoul, Republic of Korea.
  • Lee KT; Department of pharmaceutical Biochemistry, Kyung Hee University, Seoul, Republic of Korea; Department of Life and Nanopharmaceutical Science, Kyung Hee University, Seoul, Republic of Korea. Electronic address: ktlee@khu.ac.kr.
Chem Biol Interact ; 235: 85-94, 2015 Jun 25.
Article en En | MEDLINE | ID: mdl-25913072
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Solanina / Solanum tuberosum / Lipopolisacáridos / Factor de Transcripción AP-1 / Endotoxinas / Inflamación / Macrófagos Tipo de estudio: Prognostic_studies Idioma: En Revista: Chem Biol Interact Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Solanina / Solanum tuberosum / Lipopolisacáridos / Factor de Transcripción AP-1 / Endotoxinas / Inflamación / Macrófagos Tipo de estudio: Prognostic_studies Idioma: En Revista: Chem Biol Interact Año: 2015 Tipo del documento: Article