Computation of blood flow through collateral circulation of the superficial femoral artery.
Vascular
; 24(2): 126-33, 2016 Apr.
Article
en En
| MEDLINE
| ID: mdl-25972029
ABSTRACT
OBJECTIVE:
Obliteration of collaterals during (endo)vascular treatment of peripheral arterial occlusive disease is considered detrimental. We use a model to calculate maximum collateral bed flow of the superficial femoral artery in order to provide insight in their hemodynamic relevance.METHOD:
A computational model was developed using digital subtraction angiographies in combination with Poiseuille's equation and Ohm's law. Lesions were divided into short and long (<15 cm and ≥15 cm, respectively) and into stenosis and occlusions. Data are presented in relation to the calculated maximum healthy superficial femoral artery flow.RESULTS:
Stenotic lesions are longer than occlusive lesions (P < 0.05) and occlusions had more and larger collaterals (P < 0.05). In all four study groups the collateral flow significantly increased the total flow (P < 0.05). The maximum collateral system flow in the stenosis and occlusion groups was 5.1% and 20.8% of healthy superficial femoral artery flow, respectively (P < 0.05), and there were no significant differences between short and long lesions (11.2% and 6.7% of healthy superficial femoral artery flow, respectively).CONCLUSION:
The maximum collateral system flow of the superficial femoral artery is only a fraction, with a maximum of one fifth, of healthy superficial femoral artery flow. Effects of collateral vessel occlusion during (endo)vascular treatment may therefore be without detrimental consequences.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Simulación por Computador
/
Circulación Colateral
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Arteria Femoral
/
Enfermedad Arterial Periférica
/
Modelos Cardiovasculares
Tipo de estudio:
Observational_studies
Idioma:
En
Revista:
Vascular
Asunto de la revista:
ANGIOLOGIA
/
CARDIOLOGIA
Año:
2016
Tipo del documento:
Article