The role of cyclooxygenase-2, interleukin-1ß and fibroblast growth factor-2 in the activation of matrix metalloproteinase-1 in sheared-chondrocytes and articular cartilage.

Guan, Pei-Pei; Guo, Jing-Wen; Yu, Xin; Wang, Yue; Wang, Tao; Konstantopoulos, Konstantinos; Wang, Zhan-You; Wang, Pu

Guan, Pei-Pei; Guo, Jing-Wen; Yu, Xin; Wang, Yue; Wang, Tao; Konstantopoulos, Konstantinos; Wang, Zhan-You; Wang, Pu.

Afiliación

Guan PP; College of Life and Health Sciences, Northeastern University, Shenyang, P. R. China, 110819.
Guo JW; College of Life and Health Sciences, Northeastern University, Shenyang, P. R. China, 110819.
Yu X; College of Life and Health Sciences, Northeastern University, Shenyang, P. R. China, 110819.
Wang Y; College of Life and Health Sciences, Northeastern University, Shenyang, P. R. China, 110819.
Wang T; College of Life and Health Sciences, Northeastern University, Shenyang, P. R. China, 110819.
Konstantopoulos K; 1] Department of Chemical and Biomolecular Engineering [2] Johns Hopkins Institute for NanoBioTechnology [3] Johns Hopkins Physical Sciences-Oncology Center [4] Center of Cancer Nanotechonology Excellence, The Johns Hopkins University, Baltimore, Maryland, United States of America, 21218.
Wang ZY; College of Life and Health Sciences, Northeastern University, Shenyang, P. R. China, 110819.
Wang P; College of Life and Health Sciences, Northeastern University, Shenyang, P. R. China, 110819.

Sci Rep ; 5: 10412, 2015 May 20.

Article en En | MEDLINE | ID: mdl-25992485

Asunto(s)

Cartílago Articular/metabolismo; Condrocitos/metabolismo; Ciclooxigenasa 2/metabolismo; Factor 2 de Crecimiento de Fibroblastos/metabolismo; Interleucina-1beta/metabolismo; Metaloproteinasa 1 de la Matriz/metabolismo; Animales; Células Cultivadas; Condrocitos/citología; Ciclooxigenasa 2/genética; Dinoprostona/metabolismo; Dinoprostona/farmacología; Factor 2 de Crecimiento de Fibroblastos/farmacología; Humanos; Interleucina-1beta/farmacología; Proteínas Quinasas JNK Activadas por Mitógenos/metabolismo; Ratones; Ratones Transgénicos; FN-kappa B/metabolismo; Fosfatidilinositol 3-Quinasas/metabolismo; Prostaglandina D2/análogos & derivados; Prostaglandina D2/metabolismo; Prostaglandina D2/farmacología; Proteínas Proto-Oncogénicas c-akt/metabolismo; Resistencia al Corte; Transducción de Señal/efectos de los fármacos; Proteínas Quinasas p38 Activadas por Mitógenos/metabolismo

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cartílago Articular / Factor 2 de Crecimiento de Fibroblastos / Condrocitos / Metaloproteinasa 1 de la Matriz / Ciclooxigenasa 2 / Interleucina-1beta Tipo de estudio: Prognostic_studies Idioma: En Revista: Sci Rep Año: 2015 Tipo del documento: Article

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