Crystal structure of human nicotinic acid phosphoribosyltransferase.

Marletta, Ada Serena; Massarotti, Alberto; Orsomando, Giuseppe; Magni, Giulio; Rizzi, Menico; Garavaglia, Silvia.

Afiliación

Marletta AS; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.
Massarotti A; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.
Orsomando G; Department of Clinical Sciences, Section of Biochemistry, Polytechnic University of Marche, Via Ranieri 67, 60131 Ancona, Italy.
Magni G; Department of Clinical Sciences, Section of Biochemistry, Polytechnic University of Marche, Via Ranieri 67, 60131 Ancona, Italy.
Rizzi M; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.
Garavaglia S; Department of Pharmaceutical Sciences, University of Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.

FEBS Open Bio ; 5: 419-28, 2015.

Article en En | MEDLINE | ID: mdl-26042198

Palabras clave

FK866; NAD biosynthesis; NAD, nicotinamide adenine dinucleotide; NMN, nicotinamide mononucleotide; NMNAT, nicotinamide mononucleotide adenylyltransferase; Na, nicotinic acid; NaAD, nicotinic acid dinucleotide; NaMN, nicotinic acid mononucleotide; NaPRTase, nicotinic acid phosphoribosyltransferase; NamR, nicotinamide riboside; Nicotinic Acid; PRPP, 5-phosphoribosyl-1-pyrophosphate; Phosphoribosyltransferase; PreissHandler pathway; QA, quinolinic acid; Recycling NAD pathway