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The oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo.
Suijker, Johnny; Baelde, Hans J; Roelofs, Helene; Cleton-Jansen, Anne-Marie; Bovée, Judith V M G.
Afiliación
  • Suijker J; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
  • Baelde HJ; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
  • Roelofs H; Department of Immuno-Haematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
  • Cleton-Jansen AM; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
  • Bovée JV; Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Oncotarget ; 6(17): 14832-42, 2015 Jun 20.
Article en En | MEDLINE | ID: mdl-26046462
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Osteoblastos / Diferenciación Celular / Glutaratos / Isocitrato Deshidrogenasa Idioma: En Revista: Oncotarget Año: 2015 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Osteoblastos / Diferenciación Celular / Glutaratos / Isocitrato Deshidrogenasa Idioma: En Revista: Oncotarget Año: 2015 Tipo del documento: Article