Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry.

Cammarata, Michael B; Thyer, Ross; Rosenberg, Jake; Ellington, Andrew; Brodbelt, Jennifer S

Cammarata, Michael B; Thyer, Ross; Rosenberg, Jake; Ellington, Andrew; Brodbelt, Jennifer S.

Afiliación

Cammarata MB; Department of Chemistry and Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, United States.
Thyer R; Department of Chemistry and Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, United States.
Rosenberg J; Department of Chemistry and Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, United States.
Ellington A; Department of Chemistry and Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, United States.
Brodbelt JS; Department of Chemistry and Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, Texas 78712, United States.

J Am Chem Soc ; 137(28): 9128-35, 2015 Jul 22.

Article en En | MEDLINE | ID: mdl-26125523

Asunto(s)

Escherichia coli/enzimología; Espectrometría de Masas/métodos; Tetrahidrofolato Deshidrogenasa/química; Sitios de Unión; Escherichia coli/química; Escherichia coli/metabolismo; Antagonistas del Ácido Fólico/química; Antagonistas del Ácido Fólico/farmacología; Ligandos; Metotrexato/química; Metotrexato/farmacología; Modelos Moleculares; NADP/química; NADP/metabolismo; Procesos Fotoquímicos; Tetrahidrofolato Deshidrogenasa/metabolismo; Rayos Ultravioleta

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Espectrometría de Masas / Tetrahidrofolato Deshidrogenasa / Escherichia coli Tipo de estudio: Prognostic_studies Idioma: En Revista: J Am Chem Soc Año: 2015 Tipo del documento: Article

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