Identification of novel microsatellite markers <1 Mb from the HBB gene and development of a single-tube pentadecaplex PCR panel of highly polymorphic markers for preimplantation genetic diagnosis of beta-thalassemia.

Chen, Min; Tan, Arnold S C; Cheah, Felicia S H; Saw, Eugene E L; Chong, Samuel S

Chen, Min; Tan, Arnold S C; Cheah, Felicia S H; Saw, Eugene E L; Chong, Samuel S.

Afiliación

Chen M; Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Tan AS; Department of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Cheah FS; Preimplantation Genetic Diagnosis Center, Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore.
Saw EE; Preimplantation Genetic Diagnosis Center, Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore.
Chong SS; Preimplantation Genetic Diagnosis Center, Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore.

Electrophoresis ; 36(23): 2914-24, 2015 Dec.

Article en En | MEDLINE | ID: mdl-26331357

Asunto(s)

Reacción en Cadena de la Polimerasa/métodos; Diagnóstico Preimplantación/métodos; Globinas beta/genética; Talasemia beta/diagnóstico; Femenino; Frecuencia de los Genes; Humanos; Repeticiones de Microsatélite; Polimorfismo Genético; Embarazo; Talasemia beta/genética

Palabras clave

Beta-thalassemia; Linkage analysis; Microsatellite marker; Multiplex PCR; Preimplantation genetic diagnosis (PGD)

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Reacción en Cadena de la Polimerasa / Talasemia beta / Diagnóstico Preimplantación / Globinas beta Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Electrophoresis Año: 2015 Tipo del documento: Article

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