Prosaposin activates the androgen receptor and potentiates resistance to endocrine treatment in breast cancer.

Ali, Azlena; Creevey, Laura; Hao, Yuan; McCartan, Damian; O'Gaora, Peadar; Hill, Arnold; Young, Leonie; McIlroy, Marie

Ali, Azlena; Creevey, Laura; Hao, Yuan; McCartan, Damian; O'Gaora, Peadar; Hill, Arnold; Young, Leonie; McIlroy, Marie.

Afiliación

Ali A; Endocrine Oncology Research, Department of Surgery, Royal College of Surgeons in Ireland, St. Stephens Green, Dublin 2, Ireland. azlenaali@rcsi.ie.
Creevey L; Department of Surgery, Beaumont Hospital, Dublin 9, Ireland. azlenaali@rcsi.ie.
Hao Y; Endocrine Oncology Research, Department of Surgery, Royal College of Surgeons in Ireland, St. Stephens Green, Dublin 2, Ireland. lauracreevey@rcsi.ie.
McCartan D; School of Medicine and Medical Science, UCD Conway Institute, University College Dublin, Dublin, Ireland. yhao@cshl.edu.
O'Gaora P; Endocrine Oncology Research, Department of Surgery, Royal College of Surgeons in Ireland, St. Stephens Green, Dublin 2, Ireland. damiamccartan@rcsi.ie.
Hill A; School of Medicine and Medical Science, UCD Conway Institute, University College Dublin, Dublin, Ireland. peadar.ogaora@ucd.ie.
Young L; Endocrine Oncology Research, Department of Surgery, Royal College of Surgeons in Ireland, St. Stephens Green, Dublin 2, Ireland. adkhill@rcsi.ie.
McIlroy M; Department of Surgery, Beaumont Hospital, Dublin 9, Ireland. adkhill@rcsi.ie.

Breast Cancer Res ; 17: 123, 2015 Sep 04.

Article en En | MEDLINE | ID: mdl-26341737

Asunto(s)

Inhibidores de la Aromatasa/farmacología; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/genética; Resistencia a Antineoplásicos/genética; Receptores Androgénicos/genética; Saposinas/genética; Antineoplásicos Hormonales/farmacología; Línea Celular Tumoral; Movimiento Celular/efectos de los fármacos; Movimiento Celular/genética; Supervivencia sin Enfermedad; Femenino; Proteínas de Homeodominio/genética; Humanos; Células MCF-7; Masculino; Neoplasias de la Próstata/genética; ARN Mensajero/genética; Tamoxifeno/farmacología

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptores Androgénicos / Resistencia a Antineoplásicos / Saposinas / Inhibidores de la Aromatasa Tipo de estudio: Prognostic_studies / Systematic_reviews Idioma: En Revista: Breast Cancer Res Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article

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