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NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.
Garcia-Rendueles, Maria E R; Ricarte-Filho, Julio C; Untch, Brian R; Landa, Inigo; Knauf, Jeffrey A; Voza, Francesca; Smith, Vicki E; Ganly, Ian; Taylor, Barry S; Persaud, Yogindra; Oler, Gisele; Fang, Yuqiang; Jhanwar, Suresh C; Viale, Agnes; Heguy, Adriana; Huberman, Kety H; Giancotti, Filippo; Ghossein, Ronald; Fagin, James A.
Afiliación
  • Garcia-Rendueles ME; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Ricarte-Filho JC; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Untch BR; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Landa I; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Knauf JA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Voza F; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Smith VE; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Ganly I; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Taylor BS; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Persaud Y; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Oler G; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Fang Y; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Jhanwar SC; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Viale A; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Heguy A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Huberman KH; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Giancotti F; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Medicine, Weill Cornell Medical College, New York, New York.
  • Ghossein R; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Fagin JA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York. Department of Medicine, Weill Cor
Cancer Discov ; 5(11): 1178-93, 2015 Nov.
Article en En | MEDLINE | ID: mdl-26359368
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Neoplasias de la Tiroides / Proteínas Nucleares / Genes ras / Eliminación de Gen / Proteínas Quinasas Activadas por Mitógenos / Neurofibromina 2 Tipo de estudio: Prognostic_studies Idioma: En Revista: Cancer Discov Año: 2015 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Factores de Transcripción / Neoplasias de la Tiroides / Proteínas Nucleares / Genes ras / Eliminación de Gen / Proteínas Quinasas Activadas por Mitógenos / Neurofibromina 2 Tipo de estudio: Prognostic_studies Idioma: En Revista: Cancer Discov Año: 2015 Tipo del documento: Article