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Molecular analyses of juvenile granulosa cell tumors bearing AKT1 mutations provide insights into tumor biology and therapeutic leads.
Auguste, Aurélie; Bessière, Laurianne; Todeschini, Anne-Laure; Caburet, Sandrine; Sarnacki, Sabine; Prat, Jaime; D'angelo, Emanuela; De La Grange, Pierre; Ariste, Olivier; Lemoine, Fréderic; Legois, Bérangère; Sultan, Charles; Zider, Alain; Galmiche, Louise; Kalfa, Nicolas; Veitia, Reiner A.
Afiliación
  • Auguste A; Institut Jacques Monod, Université Paris Diderot, CNRS UMR7592, Paris 75013, France, Faculty of Biological Sciences, Université Paris Diderot-Paris VII, 75205 Paris, France.
  • Bessière L; Institut Jacques Monod, Université Paris Diderot, CNRS UMR7592, Paris 75013, France, Faculty of Biological Sciences, Université Paris Diderot-Paris VII, 75205 Paris, France.
  • Todeschini AL; Institut Jacques Monod, Université Paris Diderot, CNRS UMR7592, Paris 75013, France, Faculty of Biological Sciences, Université Paris Diderot-Paris VII, 75205 Paris, France, veitia.reiner@ijm.univ-paris-diderot.fr todeschini@ijm.univ-paris-diderot.fr.
  • Caburet S; Institut Jacques Monod, Université Paris Diderot, CNRS UMR7592, Paris 75013, France, Faculty of Biological Sciences, Université Paris Diderot-Paris VII, 75205 Paris, France.
  • Sarnacki S; Hôpital Necker-Enfants Malades, Paris, France, Faculty of Medicine, Université Paris Descartes-Paris V, 75015 Paris, France.
  • Prat J; Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain.
  • D'angelo E; Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain.
  • De La Grange P; GenoSplice, Ltd, Paris, France.
  • Ariste O; GenoSplice, Ltd, Paris, France.
  • Lemoine F; GenoSplice, Ltd, Paris, France.
  • Legois B; Institut Jacques Monod, Université Paris Diderot, CNRS UMR7592, Paris 75013, France, Faculty of Biological Sciences, Université Paris Diderot-Paris VII, 75205 Paris, France.
  • Sultan C; Deparment of Pediatic Endocrinology, University Hospital of Montpellier, Montpellier, France and Deparment of Pediatic Surgery, Hôpital Lapeyronie, CHU Montpellier et Université de Montpellier, Montpellier, France.
  • Zider A; Institut Jacques Monod, Université Paris Diderot, CNRS UMR7592, Paris 75013, France, Faculty of Biological Sciences, Université Paris Diderot-Paris VII, 75205 Paris, France.
  • Galmiche L; Hôpital Necker-Enfants Malades, Paris, France, Faculty of Medicine, Université Paris Descartes-Paris V, 75015 Paris, France.
  • Kalfa N; Deparment of Pediatic Endocrinology, University Hospital of Montpellier, Montpellier, France and Deparment of Pediatic Surgery, Hôpital Lapeyronie, CHU Montpellier et Université de Montpellier, Montpellier, France.
  • Veitia RA; Institut Jacques Monod, Université Paris Diderot, CNRS UMR7592, Paris 75013, France, Faculty of Biological Sciences, Université Paris Diderot-Paris VII, 75205 Paris, France, veitia.reiner@ijm.univ-paris-diderot.fr todeschini@ijm.univ-paris-diderot.fr.
Hum Mol Genet ; 24(23): 6687-98, 2015 Dec 01.
Article en En | MEDLINE | ID: mdl-26362254
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Proteínas Proto-Oncogénicas c-akt / Tumor de Células de la Granulosa / Mutación Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Proteínas Proto-Oncogénicas c-akt / Tumor de Células de la Granulosa / Mutación Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2015 Tipo del documento: Article