RNA and protein expression of herpesvirus entry mediator (HVEM) is associated with molecular markers, immunity-related pathways and relapse-free survival of patients with AML.

Lichtenegger, Felix S; Kondla, Isabell; Krempasky, Michael; Weber, Anna L; Herold, Tobias; Krupka, Christina; Spiekermann, Karsten; Schneider, Stephanie; Büchner, Thomas; Berdel, Wolfgang E; Wörmann, Bernhard J; Hiddemann, Wolfgang; Subklewe, Marion

Lichtenegger, Felix S; Kondla, Isabell; Krempasky, Michael; Weber, Anna L; Herold, Tobias; Krupka, Christina; Spiekermann, Karsten; Schneider, Stephanie; Büchner, Thomas; Berdel, Wolfgang E; Wörmann, Bernhard J; Hiddemann, Wolfgang; Subklewe, Marion.

Afiliación

Lichtenegger FS; Department of Internal Medicine III, Klinikum der Universität München, Marchioninistraße 15, 81377, Munich, Germany. Felix.Lichtenegger@med.uni-muenchen.de.
Kondla I; Clinical Cooperation Group Immunotherapy, Helmholtz Zentrum München, Munich, Germany. Felix.Lichtenegger@med.uni-muenchen.de.
Krempasky M; Division of Clinical Pharmacology, Department of Internal Medicine IV, Klinikum der Universität München, Munich, Germany. Felix.Lichtenegger@med.uni-muenchen.de.
Weber AL; Department of Internal Medicine III, Klinikum der Universität München, Marchioninistraße 15, 81377, Munich, Germany.
Herold T; Clinical Cooperation Group Immunotherapy, Helmholtz Zentrum München, Munich, Germany.
Krupka C; Department of Internal Medicine III, Klinikum der Universität München, Marchioninistraße 15, 81377, Munich, Germany.
Spiekermann K; Clinical Cooperation Group Immunotherapy, Helmholtz Zentrum München, Munich, Germany.
Schneider S; Department of Internal Medicine III, Klinikum der Universität München, Marchioninistraße 15, 81377, Munich, Germany.
Büchner T; Clinical Cooperation Group Immunotherapy, Helmholtz Zentrum München, Munich, Germany.
Berdel WE; Department of Internal Medicine III, Klinikum der Universität München, Marchioninistraße 15, 81377, Munich, Germany.
Wörmann BJ; Clinical Cooperation Group Pathogenesis of Acute Leukemia, Helmholtz Zentrum München, Munich, Germany.
Hiddemann W; Department of Internal Medicine III, Klinikum der Universität München, Marchioninistraße 15, 81377, Munich, Germany.
Subklewe M; Clinical Cooperation Group Immunotherapy, Helmholtz Zentrum München, Munich, Germany.

Cancer Immunol Immunother ; 64(12): 1505-15, 2015 Dec.

Article en En | MEDLINE | ID: mdl-26377688

Asunto(s)

Biomarcadores de Tumor/genética; Regulación Neoplásica de la Expresión Génica; Leucemia Mieloide Aguda/genética; Miembro 14 de Receptores del Factor de Necrosis Tumoral/genética; Adulto; Anciano; Anciano de 80 o más Años; Médula Ósea/metabolismo; Supervivencia sin Enfermedad; Femenino; Citometría de Flujo; Humanos; Leucemia Mieloide Aguda/diagnóstico; Leucemia Mieloide Aguda/inmunología; Leucemia Mieloide Aguda/mortalidad; Masculino; Persona de Mediana Edad; Nucleofosmina; ARN/genética; Miembro 14 de Receptores del Factor de Necrosis Tumoral/inmunología

Palabras clave

Acute myeloid leukemia (AML); Costimulation; Gene expression analysis; Herpesvirus entry mediator (HVEM); Immune checkpoint molecules; Immunophenotyping

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Miembro 14 de Receptores del Factor de Necrosis Tumoral Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2015 Tipo del documento: Article

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