Induction of methionine adenosyltransferase 2A in tamoxifen-resistant breast cancer cells.

Phuong, Nguyen Thi Thuy; Kim, Sang Kyum; Im, Ji Hye; Yang, Jin Won; Choi, Min Chang; Lim, Sung Chul; Lee, Kwang Yeol; Kim, Young-Mi; Yoon, Jeong Hoon; Kang, Keon Wook

Phuong, Nguyen Thi Thuy; Kim, Sang Kyum; Im, Ji Hye; Yang, Jin Won; Choi, Min Chang; Lim, Sung Chul; Lee, Kwang Yeol; Kim, Young-Mi; Yoon, Jeong Hoon; Kang, Keon Wook.

Afiliación

Phuong NT; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, South Korea.
Kim SK; College of Pharmacy, Chungnam National University, Daejeon 305-764, South Korea.
Im JH; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, South Korea.
Yang JW; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, South Korea.
Choi MC; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, South Korea.
Lim SC; Department of Pathology, College of Medicine, Chosun University, Gwangju 501-759, South Korea.
Lee KY; College of Pharmacy, Chonnam National University, Gwangju 500-757, South Korea.
Kim YM; College of Pharmacy, Hanyang University, Ansan 426-791, South Korea.
Yoon JH; Department of Oral & Maxillofacial Pathology, College of Dentistry, Daejeon Dental Hospital, Wonkwang University, Daejeon 302-120, South Korea.
Kang KW; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 151-742, South Korea.

Oncotarget ; 7(12): 13902-16, 2016 Mar 22.

Article en En | MEDLINE | ID: mdl-26418898

Asunto(s)

Neoplasias de la Mama/patología; Resistencia a Antineoplásicos; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Metionina Adenosiltransferasa/metabolismo; MicroARNs/genética; Tamoxifeno/farmacología; Antineoplásicos Hormonales/farmacología; Apoptosis; Biomarcadores de Tumor/genética; Biomarcadores de Tumor/metabolismo; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/genética; Proliferación Celular; Metilación de ADN; Femenino; Humanos; Metionina Adenosiltransferasa/genética; Factor 2 Relacionado con NF-E2/genética; Factor 2 Relacionado con NF-E2/metabolismo; FN-kappa B/genética; FN-kappa B/metabolismo; Fosfohidrolasa PTEN/genética; Fosfohidrolasa PTEN/metabolismo; Regiones Promotoras Genéticas; S-Adenosilmetionina/metabolismo; Transducción de Señal; Factor de Transcripción AP-1/genética; Factor de Transcripción AP-1/metabolismo; Células Tumorales Cultivadas

Palabras clave

MAT2A; NF-κB; PTEN; miR-146b; tamoxifen resistance

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tamoxifeno / Neoplasias de la Mama / Regulación Neoplásica de la Expresión Génica / Resistencia a Antineoplásicos / MicroARNs / Metionina Adenosiltransferasa Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article

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