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An Alternative Thiol-Reactive Dye to Analyze Ligand Interactions with the Chemokine Receptor CXCR2 Using a New Thermal Shift Assay Format.
Bergsdorf, Christian; Fiez-Vandal, Cédric; Sykes, David A; Bernet, Pascal; Aussenac, Sonia; Charlton, Steven J; Schopfer, Ulrich; Ottl, Johannes; Duckely, Myriam.
Afiliación
  • Bergsdorf C; Novartis Institutes for BioMedical Research (NIBR), Center for Proteomic Chemistry, Switzerland christian.bergsdorf@novartis.com.
  • Fiez-Vandal C; Novartis Institutes for BioMedical Research (NIBR), Center for Proteomic Chemistry, Switzerland Current affiliation: Heptares Therapeutics Ltd, BioPark, Welwyn Garden City, Hertfordshire, UK.
  • Sykes DA; Novartis Institutes for BioMedical Research (NIBR), Respiratory Diseases, Horsham, UK Current affiliation: School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
  • Bernet P; Novartis Institutes for BioMedical Research (NIBR), Center for Proteomic Chemistry, Switzerland.
  • Aussenac S; Novartis Institutes for BioMedical Research (NIBR), Center for Proteomic Chemistry, Switzerland Current affiliation: Novartis Pharma, Basel, Switzerland.
  • Charlton SJ; Novartis Institutes for BioMedical Research (NIBR), Respiratory Diseases, Horsham, UK Current affiliation: School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
  • Schopfer U; Novartis Institutes for BioMedical Research (NIBR), Center for Proteomic Chemistry, Switzerland.
  • Ottl J; Novartis Institutes for BioMedical Research (NIBR), Center for Proteomic Chemistry, Switzerland.
  • Duckely M; Novartis Institutes for BioMedical Research (NIBR), Center for Proteomic Chemistry, Switzerland.
J Biomol Screen ; 21(3): 243-51, 2016 Mar.
Article en En | MEDLINE | ID: mdl-26644402
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Compuestos de Sulfhidrilo / Receptores de Interleucina-8B / Colorantes / Descubrimiento de Drogas / Fluorometría / Ligandos Idioma: En Revista: J Biomol Screen Asunto de la revista: BIOLOGIA MOLECULAR Año: 2016 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Compuestos de Sulfhidrilo / Receptores de Interleucina-8B / Colorantes / Descubrimiento de Drogas / Fluorometría / Ligandos Idioma: En Revista: J Biomol Screen Asunto de la revista: BIOLOGIA MOLECULAR Año: 2016 Tipo del documento: Article