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Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism.
Probert, Philip M; Palmer, Jeremy M; Alhusainy, Wasma; Amer, Aimen O; Rietjens, Ivonne M C M; White, Steven A; Jones, David E; Wright, Matthew C.
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  • Probert PM; Institute Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.
  • Palmer JM; Institute Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.
  • Alhusainy W; Division of Toxicology, Wageningen University, Tuinlaan 5, 6703HE Wageningen, The Netherlands.
  • Amer AO; Institute Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.
  • Rietjens IM; Division of Toxicology, Wageningen University, Tuinlaan 5, 6703HE Wageningen, The Netherlands.
  • White SA; Institute Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.
  • Jones DE; Institute Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.
  • Wright MC; Institute Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom. Electronic address: M.C.Wright@ncl.ac.uk.
Toxicol Lett ; 243: 98-110, 2016 Jan 22.
Article en En | MEDLINE | ID: mdl-26739637
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Daño del ADN / Sulfotransferasas / Hepatocitos / Anisoles Idioma: En Revista: Toxicol Lett Año: 2016 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Daño del ADN / Sulfotransferasas / Hepatocitos / Anisoles Idioma: En Revista: Toxicol Lett Año: 2016 Tipo del documento: Article