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A new GLP-1 analogue with prolonged glucose-lowering activity in vivo via backbone-based modification at the N-terminus.
Bai, Xiaohui; Niu, Youhong; Zhu, Jingjing; Yang, An-Qi; Wu, Yan-Fen; Ye, Xin-Shan.
Afiliación
  • Bai X; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd No. 38, Beijing 100191, PR China.
  • Niu Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd No. 38, Beijing 100191, PR China.
  • Zhu J; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd No. 38, Beijing 100191, PR China.
  • Yang AQ; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd No. 38, Beijing 100191, PR China.
  • Wu YF; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd No. 38, Beijing 100191, PR China. Electronic address: wuyanfen@pku.edu.cn.
  • Ye XS; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd No. 38, Beijing 100191, PR China. Electronic address: xinshan@bjmu.edu.cn.
Bioorg Med Chem ; 24(6): 1163-70, 2016 Mar 15.
Article en En | MEDLINE | ID: mdl-26895657
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Glucemia / Diabetes Mellitus Tipo 2 / Péptido 1 Similar al Glucagón / Hipoglucemiantes Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Glucemia / Diabetes Mellitus Tipo 2 / Péptido 1 Similar al Glucagón / Hipoglucemiantes Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2016 Tipo del documento: Article