[Bone Marrow Microenvironment and Myelodysplastic Syndromes--Review].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
; 24(1): 290-4, 2016 Feb.
Article
en Zh
| MEDLINE
| ID: mdl-26913439
ABSTRACT
Myelodysplastic syndromes (MDS) are a group of bone marrow failure diseases. The bone marrow microenvironment consists of bone marrow stromal cells (BMSC), growth factors and cytokines. The BMSC supporting haemopoiesis include mesenchymal stem cells (MSC), osteoblasts, endothelial cells and macrophages, but the adipocytes play a role in the suppression of hematopoiesis. Recently more and more researches indicate that the abnormality of bone marrow microenvironment involves in the pathogenesis and progression of MDS. In this review the abnormality of MDS bone marrow microenvironment is summarized briefly.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Médula Ósea
/
Síndromes Mielodisplásicos
/
Microambiente Celular
Idioma:
Zh
Revista:
Zhongguo Shi Yan Xue Ye Xue Za Zhi
Asunto de la revista:
HEMATOLOGIA
Año:
2016
Tipo del documento:
Article