Exendin-4 Reverses Biochemical and Functional Alterations in the Blood-Brain and Blood-CSF Barriers in Diabetic Rats.

Zanotto, Caroline; Simão, Fabrício; Gasparin, Manuela Sangalli; Biasibetti, Regina; Tortorelli, Lucas Silva; Nardin, Patrícia; Gonçalves, Carlos-Alberto

Zanotto, Caroline; Simão, Fabrício; Gasparin, Manuela Sangalli; Biasibetti, Regina; Tortorelli, Lucas Silva; Nardin, Patrícia; Gonçalves, Carlos-Alberto.

Afiliación

Zanotto C; Biochemistry Department, Basic Sciences Institute of Health, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Simão F; Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Gasparin MS; Biochemistry Department, Basic Sciences Institute of Health, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Biasibetti R; Biochemistry Department, Basic Sciences Institute of Health, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Tortorelli LS; Biochemistry Department, Basic Sciences Institute of Health, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Nardin P; Biochemistry Department, Basic Sciences Institute of Health, Federal University of Rio Grande do Sul, Porto Alegre, Brazil. patricianardin@gmail.com.
Gonçalves CA; Biochemistry Department, Basic Sciences Institute of Health, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

Mol Neurobiol ; 54(3): 2154-2166, 2017 04.

Article en En | MEDLINE | ID: mdl-26927659

Asunto(s)

Barrera Hematoencefálica/efectos de los fármacos; Encéfalo/efectos de los fármacos; Diabetes Mellitus Experimental/metabolismo; Péptidos/farmacología; Ponzoñas/farmacología; Animales; Acuaporina 4/metabolismo; Transporte Biológico/efectos de los fármacos; Barrera Hematoencefálica/metabolismo; Encéfalo/metabolismo; Diabetes Mellitus Experimental/líquido cefalorraquídeo; Exenatida; Masculino; Ratas; Uniones Estrechas/efectos de los fármacos; Uniones Estrechas/metabolismo

Palabras clave

Bloodbrain barrier; Bloodcerebrospinal fluid barrier; Cognitive impairment; Diabetes mellitus; GLP-1 agonist

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Péptidos / Ponzoñas / Encéfalo / Barrera Hematoencefálica / Diabetes Mellitus Experimental Idioma: En Revista: Mol Neurobiol Asunto de la revista: BIOLOGIA MOLECULAR / NEUROLOGIA Año: 2017 Tipo del documento: Article

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