Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor.

Mitchell, Lorna H; Boriack-Sjodin, P Ann; Smith, Sherri; Thomenius, Michael; Rioux, Nathalie; Munchhof, Michael; Mills, James E; Klaus, Christine; Totman, Jennifer; Riera, Thomas V; Raimondi, Alejandra; Jacques, Suzanne L; West, Kip; Foley, Megan; Waters, Nigel J; Kuntz, Kevin W; Wigle, Tim J; Scott, Margaret Porter; Copeland, Robert A; Smith, Jesse J; Chesworth, Richard

Mitchell, Lorna H; Boriack-Sjodin, P Ann; Smith, Sherri; Thomenius, Michael; Rioux, Nathalie; Munchhof, Michael; Mills, James E; Klaus, Christine; Totman, Jennifer; Riera, Thomas V; Raimondi, Alejandra; Jacques, Suzanne L; West, Kip; Foley, Megan; Waters, Nigel J; Kuntz, Kevin W; Wigle, Tim J; Scott, Margaret Porter; Copeland, Robert A; Smith, Jesse J; Chesworth, Richard.

Afiliación

Mitchell LH; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Boriack-Sjodin PA; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Smith S; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Thomenius M; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Rioux N; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Munchhof M; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Mills JE; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Klaus C; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Totman J; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Riera TV; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Raimondi A; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Jacques SL; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
West K; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Foley M; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Waters NJ; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Kuntz KW; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Wigle TJ; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Scott MP; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Copeland RA; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Smith JJ; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.
Chesworth R; Epizyme Inc. , Fourth Floor, 400 Technology Square, Cambridge, Massachusetts 02139, United States.