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T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.
Martin, Bradley N; Wang, Chenhui; Zhang, Cun-jin; Kang, Zizhen; Gulen, Muhammet Fatih; Zepp, Jarod A; Zhao, Junjie; Bian, Guanglin; Do, Jeong-su; Min, Booki; Pavicic, Paul G; El-Sanadi, Caroline; Fox, Paul L; Akitsu, Aoi; Iwakura, Yoichiro; Sarkar, Anasuya; Wewers, Mark D; Kaiser, William J; Mocarski, Edward S; Rothenberg, Marc E; Hise, Amy G; Dubyak, George R; Ransohoff, Richard M; Li, Xiaoxia.
Afiliación
  • Martin BN; Department of Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Wang C; Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Zhang CJ; Department of Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Kang Z; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
  • Gulen MF; Department of Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Zepp JA; Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.
  • Zhao J; Department of Immunology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.
  • Bian G; Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine, Shanghai, China.
  • Do JS; Department of Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Min B; Department of Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Pavicic PG; Department of Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • El-Sanadi C; Department of Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Fox PL; Department of Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Akitsu A; Department of Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Iwakura Y; Department of Immunology, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Sarkar A; Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
  • Wewers MD; Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, USA.
  • Kaiser WJ; Research Institute for Biomedical Sciences, Tokyo University of Science, Yamazaki, Noda, Japan.
  • Mocarski ES; Research Institute for Biomedical Sciences, Tokyo University of Science, Yamazaki, Noda, Japan.
  • Rothenberg ME; Davis Heart and Lung Research Institute, Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Hise AG; Davis Heart and Lung Research Institute, Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Dubyak GR; Department of Microbiology and Immunology, Emory Vaccine Center, Atlanta, Georgia, USA.
  • Ransohoff RM; Department of Microbiology and Immunology, Emory Vaccine Center, Atlanta, Georgia, USA.
  • Li X; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Nat Immunol ; 17(5): 583-92, 2016 May.
Article en En | MEDLINE | ID: mdl-26998763
Asunto(s)
Proteínas Reguladoras de la Apoptosis/inmunología; Encefalomielitis Autoinmune Experimental/inmunología; Linfocitos T/inmunología; Células Th17/inmunología; Adenosina Trifosfato/farmacología; Animales; Proteínas Reguladoras de la Apoptosis/genética; Proteínas Reguladoras de la Apoptosis/metabolismo; Proteínas Adaptadoras de Señalización CARD; Linfocitos T CD4-Positivos/inmunología; Linfocitos T CD4-Positivos/metabolismo; Proteínas Portadoras/genética; Proteínas Portadoras/inmunología; Proteínas Portadoras/metabolismo; Caspasa 8/genética; Caspasa 8/inmunología; Caspasa 8/metabolismo; Supervivencia Celular/genética; Supervivencia Celular/inmunología; Células Cultivadas; Encefalomielitis Autoinmune Experimental/genética; Encefalomielitis Autoinmune Experimental/metabolismo; Citometría de Flujo; Expresión Génica/inmunología; Immunoblotting; Inflamasomas/genética; Inflamasomas/inmunología; Inflamasomas/metabolismo; Interleucina-17/genética; Interleucina-17/inmunología; Interleucina-17/metabolismo; Interleucina-1beta/genética; Interleucina-1beta/inmunología; Interleucina-1beta/metabolismo; Ratones Endogámicos C57BL; Ratones Noqueados; Ratones Transgénicos; Proteína con Dominio Pirina 3 de la Familia NLR; Reacción en Cadena de la Polimerasa de Transcriptasa Inversa; Transducción de Señal/genética; Transducción de Señal/inmunología; Linfocitos T/efectos de los fármacos; Linfocitos T/metabolismo; Células Th17/efectos de los fármacos; Células Th17/metabolismo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Linfocitos T / Encefalomielitis Autoinmune Experimental / Proteínas Reguladoras de la Apoptosis / Células Th17 Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2016 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Linfocitos T / Encefalomielitis Autoinmune Experimental / Proteínas Reguladoras de la Apoptosis / Células Th17 Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2016 Tipo del documento: Article