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Population variation of HLA genes in rural communities in Brazil, the Quilombos from the Vale do Ribeira, São Paulo - Brazil.
Nunes, Kelly; Piovezan, Bruno; Torres, Margareth A; Pontes, Gerlândia N; Kimura, Lilian; Carnavalli, Juliana E P; Mingroni Netto, Regina Célia; Moraes, Maria Elisa; Meyer, Diogo.
Afiliación
  • Nunes K; University of São Paulo, Department of Genetics and Evolutionary Biology, São Paulo, Brazil.
  • Piovezan B; JRM-Investigações Imunológicas, Rio de Janeiro, Brazil.
  • Torres MA; JRM-Investigações Imunológicas, Rio de Janeiro, Brazil.
  • Pontes GN; JRM-Investigações Imunológicas, Rio de Janeiro, Brazil.
  • Kimura L; University of São Paulo, Department of Genetics and Evolutionary Biology, São Paulo, Brazil.
  • Carnavalli JE; University of São Paulo, Department of Genetics and Evolutionary Biology, São Paulo, Brazil.
  • Mingroni Netto RC; University of São Paulo, Department of Genetics and Evolutionary Biology, São Paulo, Brazil.
  • Moraes ME; JRM-Investigações Imunológicas, Rio de Janeiro, Brazil.
  • Meyer D; University of São Paulo, Department of Genetics and Evolutionary Biology, São Paulo, Brazil. Electronic address: diogo@ib.usp.br.
Hum Immunol ; 77(6): 447-8, 2016 Jun.
Article en En | MEDLINE | ID: mdl-27060779
ABSTRACT
In the present study, we characterized the allelic and haplotypic profile of the genes HLA-A, -B, -C and -DRB1 (PCR-SBT) in a population sample of 144 highly admixed individuals, coming from rural communities in Brazil (Quilombos from Vale do Ribeira, in the State of São Paulo). Furthermore, we identified three individuals with a new null allele in the HLA-C gene (HLA-C(∗)02105N), associated with the haplotype HLA-A(∗)80 01∼B(∗)18 0101G∼DRB1(∗) 0701.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Población Rural / Antígenos HLA-A / Antígenos HLA-B / Antígenos HLA-C / Cadenas HLA-DRB1 País/Región como asunto: America do sul / Brasil Idioma: En Revista: Hum Immunol Año: 2016 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Población Rural / Antígenos HLA-A / Antígenos HLA-B / Antígenos HLA-C / Cadenas HLA-DRB1 País/Región como asunto: America do sul / Brasil Idioma: En Revista: Hum Immunol Año: 2016 Tipo del documento: Article