CUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesis.

Xu, Junfen; Fang, Yifeng; Wang, Xinyu; Wang, Fenfen; Tian, Qifang; Li, Ying; Xie, Xing; Cheng, Xiaodong; Lu, Weiguo

Xu, Junfen; Fang, Yifeng; Wang, Xinyu; Wang, Fenfen; Tian, Qifang; Li, Ying; Xie, Xing; Cheng, Xiaodong; Lu, Weiguo.

Afiliación

Xu J; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.
Fang Y; The Second Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China.
Wang X; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.
Wang F; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.
Tian Q; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.
Li Y; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.
Xie X; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.
Cheng X; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.
Lu W; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.

Oncotarget ; 7(21): 31520-33, 2016 May 24.

Article en En | MEDLINE | ID: mdl-27153550

Asunto(s)

Proteínas Cullin/genética; Factor de Transcripción E2F1/genética; MicroARNs/genética; Proteínas E7 de Papillomavirus/genética; Infecciones por Papillomavirus/genética; Neoplasias del Cuello Uterino/genética; Regiones no Traducidas 3'/genética; Carcinogénesis/genética; Línea Celular Tumoral; Proteínas Cullin/metabolismo; Factor de Transcripción E2F1/metabolismo; Femenino; Regulación Neoplásica de la Expresión Génica; Células HEK293; Células HeLa; Células Hep G2; Papillomavirus Humano 16/genética; Papillomavirus Humano 16/metabolismo; Papillomavirus Humano 16/fisiología; Humanos; Proteínas E7 de Papillomavirus/metabolismo; Infecciones por Papillomavirus/virología; Unión Proteica; Interferencia de ARN; Trasplante Heterólogo; Carga Tumoral/genética; Neoplasias del Cuello Uterino/patología; Neoplasias del Cuello Uterino/virología

Palabras clave

CUL2; E2F1; HPV16 E7; cervical cancer; miR-424

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias del Cuello Uterino / Infecciones por Papillomavirus / MicroARNs / Proteínas Cullin / Proteínas E7 de Papillomavirus / Factor de Transcripción E2F1 Tipo de estudio: Prognostic_studies Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article

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