Alphaherpesvirus DNA replication in dissociated human trigeminal ganglia.
J Neurovirol
; 22(5): 688-694, 2016 10.
Article
en En
| MEDLINE
| ID: mdl-27173396
ABSTRACT
Analysis of the frequency and PCR-quantifiable abundance of herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV) DNA in multiple biological replicates of cells from dissociated randomly distributed human trigeminal ganglia (TG) of four subjects revealed an increase in both parameters and in both viruses during 5 days of culture, with no further change by 10 days. Dissociated TG provides a platform to analyze initiation of latent virus DNA replication within 5 days of culture.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Activación Viral
/
Replicación Viral
/
Ganglio del Trigémino
/
Herpesvirus Humano 1
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Herpesvirus Humano 3
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Replicación del ADN
Idioma:
En
Revista:
J Neurovirol
Asunto de la revista:
NEUROLOGIA
/
VIROLOGIA
Año:
2016
Tipo del documento:
Article